PPT:Themes in B cell development (UCSF)

aspen

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Anthony DeFranco. |+ @9 F' H9 ^/ K2 g
Department of Microbiology & Immunology, University of California at San Francisco+ H" a8 R. B. b

( G1 ]1 R% _6 _& |9 O( }/ g3 IThemes include:* v3 ]2 d2 t: y$ @) L
1. Checkpoints in B cell development:  feedback from Ig gene rearrangements
6 ?. }4 m! p. f$ e  x2. Stromal environment/growth factors for B cell development) W! I# ?9 u* f
3. Lineage commitment:  transcription factors and Notch signaling
2 \& j) O( s% Y( u+ Q. y0 {* t4. Central tolerance of B cells5 Y6 }$ G  T# p- H
5. Peripheral tolerance of B cells  q8 Y: N# d" t& U
6. 3 different types of mature B cells: choice of cell fate and relative roles

hualin840518

thanks

hughliang

非常感谢！) r6 s  o, c3 p/ M, u1 w

rainsky1314

thanks very much !

刘子文

谢谢

beidouhan

好东西呢