PDF电子书：Embryonic Stem Cells – Differentiation and Pluripotent Alternatives

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7 u: X/ V9 Z1 i$ i" [/ k8 @Embryonic Stem Cells – Differentiation and Pluripotent Alternatives
- P# e9 l" x1 B! O* I. C7 j4 A# O  vEdited by Michael S. Kallos
0 M8 c. l+ e) e3 dPublished by InTech* t1 _8 ^  U" W5 u/ p
Janeza Trdine 9, 51000 Rijeka, Croatia
8 n+ S. f" @, T- T2 x' GCopyright © 2011 InTech! K) s7 ~# [2 p5 @! Q* t+ P
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Contents
8 Z) {- i' i& q  uPreface IX
" b+ J4 L: \: W! J+ R& u5 YPart 1 General Differentiation 11 z8 K, j1 P; i6 ^. y, B
Chapter 1 Role of Signaling Pathways and Epigenetic! k8 G  Z% @$ i$ [2 ~
Factors in Lineage Determination During
6 W- ]2 ~4 R2 K: WHuman Embryonic Stem Cell Differentiation 3
( w/ {8 h/ x6 i) n2 b% L8 {, j) B' k8 k# _Prasenjit Sarkar and Balaji M. Rao
. I, ?* s) j3 v3 ~& ~Chapter 2 Bioactive Lipids in Stem Cell Differentiation 33
& K* j! w$ a3 j' @7 h! @& lErhard Bieberich and Guanghu Wang
3 l1 H, ?3 ~7 q$ v# ~  R6 P  y0 oChapter 3 Retinoid Signaling is a Context-Dependent7 |2 r2 I' h* j
Regulator of Embryonic Stem Cells 55
) z9 c' J  c/ _7 [- d  A9 I" _7 EZoltan Simandi and Laszlo Nagy
/ x  Q& f1 i% h8 u) n6 |Part 2 Neural and Retinal Differentiation 79
/ J+ _' C1 y. H0 wChapter 4 Pluripotent Stem Cells as an In Vitro
1 U% D+ g, d5 U, M4 U6 E/ gModel of Neuronal Differentiation 81: X  L; N0 j: m7 ~4 z& S
Irina Kerkis, Mirian A. F. Hayashi,4 L6 F( x* {7 ?
Nelson F. Lizier, Antonio C. Cassola,
+ `* F3 L2 F" wLygia V. Pereira and Alexandre Kerkis9 D! F+ c% T0 I: L
Chapter 5 Characterization of Embryonic Stem (ES)
+ R6 T0 \0 M- k: h, ONeuronal Differentiation Combining Atomic Force,6 k. D9 M+ W" `5 r. w
Confocal and DIC Microscopy Imaging 995 Q8 Y" U3 o. B7 t$ }- G3 S3 }: j
Maria Elisabetta Ruaro, Jelena Ban and Vincent Torre- k. P1 i, y8 r. p+ d
Chapter 6 Oligodendrocyte Fate Determination
( f* l$ V# y' |$ Z8 x. K, Min Human Embryonic Stem Cells 119
0 F. ?+ t6 a2 v" k- \& @$ ySiddharth Gupta, Angelo All and Candace Kerr0 Z' q% P8 O* m. C3 o) R" u9 x
Chapter 7 Stem-Cell Therapy for Retinal Diseases 1352 L$ g& V- @! [8 v5 D+ a3 s! }
Rubens Camargo Siqueira
( m  a. g$ b+ rVI Contents) H4 ?- w& B0 ]
Part 3 Cardiac and Other Myogenic Differentiation 149
+ W7 ]) N- i) ?3 x2 PChapter 8 Transcriptional Networks
& O% V+ K* X! P) Dof Embryonic Stem Cell-Derived Cardiomyogenesis 151# j9 V1 B0 ~8 J( E2 v$ |
Diego Franco, Estefania Lozano-Velasco and Amelia Aránega
$ n  F5 y5 _% E- pChapter 9 Human Pluripotent Stem Cells( U/ m! D' ?! {; I8 O+ S) d% g
in Cardiovascular Research and Regenerative Medicine 169
. x# ^- h2 T. e/ u2 @1 sEllen Poon, Chi-wing Kong and Ronald A. Li# M; U: m' ?% u% d
Chapter 10 Human Pluripotent Stem Cell-Derived Cardiomyocytes:
1 Z' }/ x+ H2 ?/ O( dMaturity and Electrophysiology 1852 y9 v% @) Y9 s3 I
Ville Kujala, Mari Pekkanen-Mattila and Katriina Aalto-Setälä
1 k; ?  O% E5 ]2 K( Z5 YChapter 11 Maintenance Of Calcium Homeostasis
, ~4 h# W+ t$ h( V) R* Y) m$ Sin Embryonic Stem Cell-Derived Cardiomyocytes 2059 _2 D/ T" L, n" B$ o& @
Iek Chi Lo, Chun Kit Wong and Suk Ying Tsang
& q2 G+ |  L- x! |. J1 A1 XChapter 12 Myogenic Differentiation of ES Cells for Therapies
3 I6 W5 `) H2 |in Neuromuscular Diseases: Progress to Date 2278 d, g# J. @" o- Y7 B8 d, {. o" }
Camila F. Almeida, Danielle Ayub-Guerrieri and Mariz Vainzof3 M, W) `! o; m. u) \
Part 4 Endothelial Differentiation 243) |! [3 D. K4 n3 x6 [' w3 g
Chapter 13 Dissecting the Signal Transduction Pathway
7 l( Q* \& R6 C0 |  i) Mthat Directs Endothelial Differentiation Using- Q5 N  U& t: i
Embryonic Stem CellDerived Vascular Progenitor Cells 245: @/ i8 B, g4 d' s: |9 ~
Kyoko Kawasaki and Keiji Miyazawa
. ]8 h; _1 w9 m6 @3 nChapter 14 Endothelial Differentiation of Embryonic Stem Cells 267
4 g( q( A: b1 \4 @: E; k& l- z$ PPeter Oettgen: A9 k! ~/ i5 L! @( _" Y
Part 5 Hepatic Differentiation 277& n: b( k/ h+ |- W$ \
Chapter 15 Stem Cells for HUMAN Hepatic Tissue Engineering 279
, b2 D0 n' j. F& S  QN.I. Nativ, M.A. Ghodbane, T.J. Maguire,
6 p& y; o/ Y: Y0 ~! ?4 t; IF. Berthiaume and M.L. Yarmush
9 _$ {  n* d  L$ AChapter 16 Hepatic Differentiation of Human Embryonic and Induced& K/ f6 y) N* w1 r$ X
Pluripotent Stem Cells for Regenerative Medicine 303
4 f9 ]. C  B$ B1 b$ YToshio Miki
( [6 t3 J4 Y6 m6 C6 R+ YPart 6 Osteogenic Differentiation 3214 p# b" M6 m8 M  s1 v/ S/ I4 E
Chapter 17 Osteogenesis from Pluripotent Stem Cells:$ x5 X; j: F! C+ \% d: s" J
Neural Crest or Mesodermal Origin? 323
* Q5 W8 c* }- s/ @  wKevin C. Keller and Nicole I. zur Nieden% |  w9 ]4 U7 s: u; v% d- {  X
Contents VII. I5 {( O- h8 O+ q' J* }
Part 7 Pluripotent Alternatives –8 p, ?5 R0 ~( d% J8 ~% H0 u: n
Induced Pluripotent Stem Cells (iPSCs) 3495 T5 g. m+ c% b( G5 T: z
Chapter 18 The Past, Present and Future of
8 Z: ^; h! L& P& X5 uInduced Pluripotent Stem Cells 351  q/ k2 E' T: E7 S& N" P" k
Koji Tanabe and Kazutoshi Takahashi9 |, i0 u7 h: w2 p- q& R
Chapter 19 New Techniques in the Generation3 r* |$ l- w9 h2 x* O- ]
of Induced Pluripotent Stem Cells 373
( D5 T4 W  h, Z* c  u! QRaymond C.B. Wong, Ellen L. Smith and Peter J. Donovan
  i  Y0 F" j1 F# X1 [Chapter 20 Generation of ICM-Type Human iPS Cells5 u% B0 @! B1 W  b9 k
from CD34+ Cord Blood Cells 399
1 D8 O0 K: O: ~  uNaoki Nishishita, Noemi Fusaki and Shin Kawamata
' K, R6 I3 h5 JChapter 21 Modelling of Neurological Diseases5 V* b5 E- ^- W" k9 L4 h, a' J
Using Induced Pluripotent Stem Cells 4135 S/ V3 Z1 _; K6 g- S) P  n. ]
Oz Pomp, Chen Sok Lam, Hui Theng Gan,, T6 t0 G2 e) g
Srinivas Ramasamy and Sohail Ahmed
" J- f! \1 _. C. d6 f, gPart 8 Pluripotent Alternatives - Other Cell Sources 431- L3 q9 Y- \! _2 b; `% ?; a) k
Chapter 22 Very Small Embryonic/Epiblast-Like Stem Cells (VSELs)3 M2 Q9 j( w/ y# R/ L5 Z
Residing in Adult Tissues and Their Role
- M' i! r8 k* T- ~in Tissue Rejuvenation and Regeneration 433
. @  x# e0 Z% c% f" D) b+ v3 ADong-Myung Shin, Janina Ratajczak,6 W- C1 t, ]3 n( }  l2 m; b
Magda Kucia and Mariusz Z. Ratajczak: e9 u) ^, \8 `- I! z8 x# s
Chapter 23 Multipotent Dental Stem Cells:
) j  k$ C3 \6 q9 _2 LAn Alternative Adult Derived Stem- B8 g. v9 e0 V% Q0 o
Cell Source for Regenerative Medicine 451
1 K  \+ {7 B0 c7 z5 T# ATammy Laberge and Herman S. Cheung* u* L: p$ C3 \4 C% \$ `2 S9 N
Chapter 24 Pluripotent Stem Cells from Testis 473
  v" f( g5 e/ t) G8 t: XSandeep Goel and Hiroshi Imai
: b+ r' A+ C/ _: z2 sChapter 25 Amniotic Fluid Stem Cells 493+ U+ i: \& ?/ P. Y
Gianni Carraro, Orquidea H. Garcia,1 F0 ?( [  J; s3 I- T
Laura Perin, Roger De Filippo and David Warburton+ p0 b3 ^$ Z" ?

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