2013-4-18 Immunity

nero1981

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Volume 38, Issue 4
3 ~* v5 |! `7 K1 D9 ~On the cover: The lymphoid stromal microenvironment is required to provide
& G2 \5 W+ L) o2 r* U1 X: nstructural support for lymphocyte migration, localization, and function. By fate 0 O9 f/ N. Z; t9 P7 {
mapping analysis, Castagnaro et al. (pages 782–791) show that mature stromal ; Q. \! h) x0 J" y' l- m
cells originate from embryonic mesenchymal progenitors of the 3 D, d- B& ^( F2 _& P3 J* \
Nkx2-5+Islet1+ lineage. This study suggests the presence
0 _8 ^7 L  D; ~. z( n$ t* X& Yof multipotent progenitors that generate distinct stromal cell subsets and - v( z4 @( c& |' l% g
participate in lymphoid tissue remodeling and repair. The cover image depicts a   P% [8 h; P/ I
hierarchical model for generating the stromal microenvironment in development 0 \  k2 @( v, ^- ^8 X5 y" k$ ?: Z
and organ regeneration whereby the roots represent the stromal progenitors
" H* k& L! N# m4 g, Hgiving rise to fibroblastic reticular cells, follicular dendritic cells, and 0 \, d* x0 c5 g- `+ C) B  \5 C0 i7 d: O* o
marginal reticular cells as represented by the leaves. Image by Laura Castagnaro 9 g& I( C# v( ?" l: t
and Samir Khadem." Q  `+ J: ?0 G+ s

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zylucky98

laoli1999

楼上的稍等啦  

123456zsz

好人一个  

大小年

回复一下  

sky蓝

一个子 没看懂  

tuanzi

干细胞研究还要面向临床

榴榴莲

好贴坏贴，一眼就看出去  

yukun

好啊，谢楼主

命运的宠儿

很好！很强大！