DNMT关系图

Tlexander

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如图所示为DNMT的作用关系图，看看大家对此有何意见？
6 d8 ?4 ~2 w4 H! R( x$ b  Homo sapiens  DNMT1 - DNA (cytosine-5-)-methyltransferase 1; Methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2. In [...]  8 [* b+ ^, }1 w* ^" O( D* @( h
  Mus musculus  Dnmt1 - DNA methyltransferase (cytosine-5) 1 Gene; Methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2. [...]  
; ?6 T: v% _% H9 e; J$ o  Anolis carolinensis  DNMT1 - DNA (cytosine-5-)-methyltransferase 1 1 A  G$ y$ k* q; U0 ?/ A+ E. q- _
  Bos taurus  DNMT1 - DNA (cytosine-5)-methyltransferase 1 (Dnmt1)(EC 2.1.1.37); Methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct b [...]  # v# C  t4 y' K( r2 J' J
  Canis lupus familiaris  DNMT1 - DNA (cytosine-5-)-methyltransferase 1 3 D2 @: D6 j" a9 D' s# ^. D
  Cavia porcellus  DNMT1 - DNA (cytosine-5-)-methyltransferase 1
% R) ?- @9 U" w% _9 s- B9 i/ c  Danio rerio  dnmt1 - DNA (cytosine-5-)-methyltransferase 1  ) c6 ]) s4 c) B$ R0 q  Z
  Dasypus novemcinctus  DNMT1 - DNA (cytosine-5-)-methyltransferase 1
1 r, w/ n  k! H6 W5 t8 J, x; X  Felis catus  DNMT1 - DNA (cytosine-5-)-methyltransferase 1
5 f* n8 W- e9 p6 _  Gasterosteus aculeatus  DNMT1 - DNA (cytosine-5-)-methyltransferase 1
; I) k; e6 l0 n% ~0 L5 r7 R7 W  Macaca mulatta  DNMT1 - DNA (Cytosine-5)-methyltransferase 1 Fragment  ( M/ N. \$ s& [( @" g/ r
  Monodelphis domestica  DNMT1 - DNA (cytosine-5-)-methyltransferase  $ E( L: P6 W9 F/ X+ q
  Ornithorhynchus anatinus  DNMT1 - DNA (cytosine-5-)-methyltransferase 1   Z+ ?  s: t* N4 w
  Oryctolagus cuniculus  DNMT1 - DNA (cytosine-5-)-methyltransferase 1 9 c4 c% l. Z% g5 A2 _
  Oryzias latipes  DNMT1 - DNA (cytosine-5-)-methyltransferase 1
4 `* ?/ k0 t& d  Pan troglodytes  DNMT1 - DNA (cytosine-5-)-methyltransferase 1
3 j0 D, J/ x* \. K6 B  e  Pongo pygmaeus  DNMT1 - DNA (cytosine-5-)-methyltransferase 1
0 X! Q6 Q; Y% q5 `# q* R( x+ M  Rattus norvegicus  Dnmt1 - DNA (cytosine-5)-methyltransferase 1 (Dnmt1)(EC 2.1.1.37)(MCMT)(DNA methyltransferase I)(DNA MTase RnoIP)(M.RnoIP); Methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of [...]  " t8 m& G( Z$ t+ s# c) J& @, Z+ c* ?
  Sus scrofa  Dnmt1 - Cytosine-specific methyltransferase (EC 2.1.1.37)
5 {* ~5 `- R& f# C" A  Takifugu rubripes  DNMT1 - DNA (cytosine-5-)-methyltransferase 1 + V2 H! n; |* q3 Y# ]7 ^
  Tetraodon nigroviridis  DNMT1 - DNA (cytosine-5-)-methyltransferase 1 ! a. o# V, W, B
  Homo sapiens  DNMT3B - DNA (cytosine-5-)-methyltransferase 3 beta; Required for genome wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as transcriptional co- repressor by associating with CBX4 and independently of DNA methylation. Seems to be involved in gene silencing (By similarity). In association with DNMT1 and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene express [...]  * p) @3 O, X3 S: K  i3 _, g
  Canis lupus familiaris  ENSCAFG00000008367 - DNA (cytosine-5-)-methyltransferase 1 9 z9 r, ]- |! `9 O- V+ W
  Equus caballus  GLP1 - DNA (cytosine-5-)-methyltransferase 1 " A' D5 H5 D3 w
  Monodelphis domestica  ENSMODG00000005324 - DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37)
1 r, e" J/ w& v; _6 ^2 E9 n5 n# u  Sus scrofa  ENSSSCG00000013657 - DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37) , X9 G; @1 K- x  T& I
  Xenopus (Silurana) tropicalis  GLP1 - DNA (cytosine-5-)-methyltransferase 1
0 D& c" Y1 |7 c  Mus musculus  Dnmt3b - DNA methyltransferase 3B Gene; Required for genome wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as transcriptional co- repressor by associating with CBX4 and independently of DNA methylation. Seems to be involved in gene silencing. In association with DNMT1 and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by modulating dimethylati [...]  
8 }/ }. C& M8 A9 [2 [  Taeniopygia guttata  ENSTGUG00000007598 - DNA methyltransferase 1-associated protein 1 (DNMT1-associated protein 1)(DNMAP1) [Taeniopygia guttata] 0 m* q: \4 C: }* n4 ?( l
  Taeniopygia guttata  ENSTGUG00000014910 - DNA (cytosine-5)-methyltransferase 1 (Dnmt1)(EC 2.1.1.37)(MCMT)(DNA methyltransferase HsaI)(DNA MTase HsaI)(M.HsaI)(CXXC-type zinc finger protein 9) [Taeniopygia guttata]   j8 {. O& P% ^' A8 U$ z* w
  Taeniopygia guttata  ENSTGUG00000013708 - DNA (cytosine-5)-methyltransferase 1 (Dnmt1)(EC 2.1.1.37)(MCMT)(DNA methyltransferase HsaI)(DNA MTase HsaI)(M.HsaI)(CXXC-type zinc finger protein 9) [Taeniopygia guttata] * D7 H1 ]; z# V" ?  X

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mikeli

这个不错

郇延军

好东东，我怎么一直加不了你好友？

Tlexander

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  K0 J! ]9 Q1 E* {( g  u好像不能加好友吧，师兄现在在哪个所呢？

郇延军

回复 Tlexander 的帖子
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在山东农科院

Tlexander

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" S# Q' s. f5 s* Y& W哇，师兄给力，留个联系方式吧，吼一吼

郇延军

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