Adult mouse bone marrow stem cells can become cells of the nervous system

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日期: 2003-08-19 今日/总浏览: 1/435
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2 V  q( f! D( C' M" GUniversityofMinnesotaresearchersshowthatadultbonemarrowstemcellscanbeinducedtodifferentiateintocellsofthemidbrain.Thefindings,publishedintheonlineearlyeditionoftheProceedingsoftheNationalAcademyofSciences,suggestthatadultbone-marrow-derivedstemcellsmayonedaybeusefulfortreatingdiseasesofthecentralnervoussystem,includingParkinson'sdisease.; q4 D9 O$ Z# G" O) w
Thepotentialoftheseadultstemcells,termedmultipotentadultprogenitorcells(MAPCs),werethesubjectofresearchreportedinNatureinJune2002.Today'spublishedresearchfindingsshowspecificcelldifferentiationforaspecificgoal.Whilethistypeofcelldifferentiationhasbeenshowntooccurfromembryonicandneuralstemcells,thisisthefirsttimeadultbone-marrow-derivedcellshavebeenshowntogeneratedopaminelikeneurons.( I! W" ?5 g& c- _9 y) S  h) a
We'reabletoshowinvitrogenerationoffunctionaldopamineproducingcellsfromadultbonemarrowstemcellsneededfortherapyofParkinson's,saidleadinvestigatorCatherineVerfaillie,M.D.,directoroftheuniversity'sStemCellInstitute.ThisfurtherprovessimilarityoftheMAPCswithembryonicstemcells.( G, }( e; S' ~0 ~( q  B+ ]! Z
Again,whileadultstemcellsholdgreatpromise,sidebysidecomparisonofadultandembryonicstemcellsmustbedonetodeterminewhichstemcellsaremostusefulintreatingaparticulardisease,saidVerfaillie.
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来源: University of Minnesota& o# p/ T/ I7 p' x8 F4 @3 T
发布者: 亦云