stem cell news 110720-27

kittybruce

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"This enables us to produce scaffolds for cell scaffolds with a resolution of approximately one micrometer directly from dissolved proteins and polymers to exactly match our construction plan. These biomimetic scaffolds will enable us to answer many aspects of threedimensional cell growth."--Sascha Engelhardt, project manager at the Fraunhofer Institute for Laser
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“This research suggests that stem cell therapies may one day be implemented in the clinic to provide relief to patients suffering from cognitive impairments incurred as a result of their cancer treatments. While much work remains, a clinical trial analyzing the safety of such approaches may be possible within a few years, most likely with patients afflicted with glioblastoma multiforme, a particularly aggressive and deadly form of brain cancer.”--Charles Limoli, a UCI radiation oncology professor." n6 k$ d7 E4 m/ F% E" b- N4 v

. P; r, j, B% [5 z' ?"Crucially, we were able to convert blood and blood vessel cells into heart muscle cells by flipping genetic switches controlled by Fgf. The important next step to this research will be to identify the relevant cells in the human heart and take this finding to the next level."--Dr Filipa Simoes at at the MRC Molecular Haematology Unit at the University of Oxford.
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"You don't want to slam the door on something that in 10 years may have potential for people with end‐stage disease."--Mayo Clinic lung experts, Charles Burger.2 d4 X* w+ X' f6 {* j
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"When generated from human beta cells, pluriponent stem cells maintain a 'memory' of their origins, in the proteins bound to their genes." --Prof. Shimon Efrat of Tel Aviv University's Department of Human Molecular Genetics and Biochemistry at the Sackler Faculty of Medicine.
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8 G% i. |( x/ ^: m; ]“This is as cutting edge as it gets. A non-steroidal substance which contains potentially regenerative stem cells. Pain management has been looking for this combination of properties which can hopefully achieve pain relief and tissue regeneration. It’s FDA regulated and also neither fetal nor embryonic. And it’s available at Preferred Pain Center now.” -- David Greene, MD, CEO of the Preferred Pain Center.
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"Engrafted cells migrated extensively, differentiated along glial and neuronal lineages, and expressed the activity‐regulated cytoskeleton‐associated protein (Arc), suggesting their capability to functionally integrate into the hippocampus. These data show that human neural stem cells afford a promising strategy for functionally restoring cognition in irradiated animals." --Munjal M. Acharya, PhD, of the University of California Irvine.
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  Z6 k0 u- b3 Y+ [1 q+ [/ ^/ t* A9 |"This is very relevant for diseases like Parkinson's, which likely will display only subtle phenotypes in the Petri dish. It is very important that the cells be genetically identical and have the same history, then make or remove only that mutation. If you use control cells from one person and a diseased cell from another person, it's like comparing apples and oranges."--Whitehead Founding Member Rudolf Jaenisch.
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“In an impoverished environment, instead of producing more neurons the stem cells produce more stem cells. So this suggests that in stressful conditions it may be advantageous for the brain produce a reserve of stem cells that can then be used [to provide a surge of new neurons] when the environment becomes more favorable.”--Columbia University neuroscientist Rene Hen.8 S0 H4 M# u% l% n, @: E  p  L

1 s0 e& L9 e5 W/ x& [. |"Cancer is very good at tricking the mesenchymal stem cells into doing what the cancer likes. The cancer takes the cells hostage and uses them to promote the cancer's growth."--Ronald Buckanovich, M.D., Ph.D., assistant professor of internal medicine and of obstetrics and gynecology at the U-M Medical School.! V! L8 q: R' n# I9 Y, g: B/ o
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"The reality may be more complicated than people think. What is a stem cell gene? What is a cancer gene? It may be the same thing... When you turn off p53, people think the cell becomes cancerous because we tend to focus on the bad thing. Actually, the cell becomes more plastic and could do good things, too. Let's say the cell is like a person who loses his job (the restriction of p53). He could become a criminal or he could find another job and have a positive effect on society. What pushes him one way or the other, we don't know because the environment is very complicated."--Jiang F. Zhong, Ph.D., assistant professor of pathology at the Keck School.
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This issue:( j% t7 f4 ~! ~- h; a

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Video news:
  R7 n; l! l! b2 K' o4 ]Skins Cells May Take the Place of Embryonic Stem Cells
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Huntsville doctors among the first to use new stem cell procedure% C! o4 W/ y) j* {$ L8 `* }; |' a; Z& I
http://www.waff.com/story/15151688/save
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