stem cell news 110529-0602

kittybruce

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"We were very surprised to find such a clear correlation between the quantity of functional telomerase, the severity of the cellular defect and the severity of the patient's clinical symptoms. Our work suggests that, in patients with dyskeratosis congenita, tissue stem cells are losing their ability to self-renew throughout the body. This is a new, unifying way to think about this disease, and it has important implications for many other conditions."-- associate professor of medicine Steven Artandi, MD, PhD. from Stanford University School of Medicine.1 B* b; l6 m8 Y# V2 E3 o# f
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“The ability to derive and grow human pluripotent stem cells in the laboratory has raised enormous expectations within the biomedical community due to their transplantational potential in clinical settings. This, when combined with the development of efficient and safe gene editing technologies in human stem cells may greatly help the realization of these expectations.” --Izpisúa Belmonte, a professor in the Gene Expression Laboratory at Salk Institute for Biological Studies.) \4 e" ~" K6 V. D& h# W1 w

* q$ w; g1 w7 E"What they're really injecting is fat ‐and yes it has some stem cells in it, but there's no advantage to the quote stem cell face lift."--Dr. Michael McGuire, past president of the American Society of Plastic Surgeons and a clinical associate professor of surgery at UCLA.
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, t2 N5 k9 G8 K% ^$ G- h“Not a lot of attention has been paid to these cells because human astrocytes have been hard to get. But we can make billions or trillions of them from a single stem cell.”--Su-Chun Zhang,  a researcher at UW-Madison’s Waisman Center and a professor of neuroscience in the UW-Madison School of Medicine and Public Health. $ K+ Z2 ?) J' l, m

' W! K/ t0 U7 H# Y) R"Normal stem cells are designed to withstand environmental insults. Thus cancer stem cells might use these same mechanisms to resist chemotherapy and radiotherapy. Remnant cancer stem cells might therefore cause tumors to relapse and re‐grow following treatment. If we could kill these cancer stem cells, we might be able to prevent relapse. Understanding the link between normal and cancerous stem cells should help us target the latter while preserving the former."--Richard Gilbertson, M.D., Ph.D., associate member of the St. Jude Developmental Neurobiology and Oncology departments.2 Z4 n- V7 [& p. c# M+ v

* ~; E. R" Q! ?$ ?3 z9 L# C“Thus, we have double proof that E-cadherin is directly associated with stem-cell pluripotency. E-Cadherin is necessary for maintaining pluripotent stem cells and also for inducing the pluripotent state in the reprogramming of somatic cells,”--Daniel Besser of the Max Delbruck Center for Molecular Medicine (MDC) Berlin-Buch.
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"It's really a patient beware situation. People actually are getting hurt in some of these clinics around the world. There have been reports of deaths."-- Larry Goldstein, director of the stem cell program at the University of California at San Diego.) b: [9 h0 @* d  S- t! s

7 F5 P9 p) V& V3 P“We were surprised that there’s a difference in the epigenetic marks in the process for liver vs. pancreas before the cell‐fate ‘decision’ is made. This suggests that we could manipulate the marks to influence fate or look at marks to better guess the fate of cells early in the differentiation process.”--Kenneth Zaret, PhD, from the University of Pennsylvania.
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6 r$ D+ k. f+ n: d: sThis issue:
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Video news:
/ T6 N1 A" ]4 R. f: x! B0 a" R4 PStem cell study brings new hope for premature babies
; F) [5 g) k3 f/ m" yhttp://www.ctv.ca/CTVNews/TopSto ... ll-research-110529/; D7 I& ]8 u. @" ?, z

( @, B: t# i4 E& ^$ M" [Renewed Hope for Stem Cell Research
4 h# Z0 t! ^7 {, ?( {4 u7 zhttp://www.redorbit.com/news/vid ... ell_research/25849/
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1 Z+ W! ]- C) P. \, ?  h8 ~Brain Tumor Breakthroughs Using Stem Cells! G2 q1 _, I0 [  D( K& B: ~! }
http://www.redorbit.com/news/vid ... g_stem_cells/33967/