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本帖最后由 kittybruce 于 2011-5-15 19:55 编辑 ' R: E5 m4 T$ @8 Z- U ]# ?
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边忙毕业边编辑新闻的人伤不起啊！积压了近10天的新闻一次出啊！快比Cell的出版速度慢了啊！有木有！
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+ J' t$ Q! C/ Z- Z& ^Voice from last issue:
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. R4 f1 d+ Z6 p/ Z) q“If I was told even five years ago that someone would simply be able to introduce a few transcription factors and a few genes into skin cells and get them to become pluripotent stem cells, I would have said that’s crazy. I thought it would take us a decade or more to figure out what we now call reprogramming and now it is a standard technique in many laboratories...I think iPS cells are very similar to embryonic stem cells and in many instances will be effective replacements. If you are looking to model certain diseases, you can do that more easily using iPS cells. However, there are certain diseases, some of which we have studied, where the iPS approach doesn’t appear to work or doesn’t give you the same kind of model as using embryonic stem cells. So, whereas I think iPS cells are extremely exciting, I don’t see them as a complete substitute for embryonic stem cells...Embryonic stem cells remain the gold standard.”--George Daley, Professor of Hematology at Harvard Medical School and Director of the Stem Cell Transplantation Program at HMMI/Children’s Hospital Boston.' x! ]7 k3 Y" S5 }+ g. k6 X
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“Although we have successfully established the first line of hES from the Brazilian population that adds to the pool of genetically different pluripotent cells available, it will be important to have access to embryos from the more mixed population and assistance from the Public Health System.”--Dr. Lygia V. Pereira of the Molecular Genetics Laboratory at the University of Sao Paulo, Brazil.( g5 Z$ f0 l5 _& u* [
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“The advantages include less ethical controversy, abundant cell availability from discarded tissues from elective surgeries like breast reductions and tummy tucks, and a much reduced possibility for immune rejection when re-implanting cells extracted from a person’s own fat.” --Dr. Juares Bianco, a postdoctoral fellow in the Department of Chemical Engineering and the Human Mobility Research Centre (HMRC) at Queen’s University.( F* J1 K' c, n4 U% b* D1 t
& F4 Z7 E7 t1 t; _, j+ X; d"If we went 10 years and had no clinical treatments, it would be a failure." --CIRM's president, Alan Trounson.7 `* g5 t/ C$ ?
; L5 S. [$ F' V; w"We found that although there are subtle molecular differences between iPSCs and ESCs, their functional potential to differentiate was virtually indistinguishable in vitro. It is important to understand that iPSCs offer many possibilities in regenerative medicine and developmental biology research and may hold the key to future medical treatments for many human diseases."--Darrell Kotton, MD, an associate professor of medicine and pathology at Boston University School of Medicine.: T J0 g& B$ Q7 a
% T/ O) n" D8 a* v, S4 q"This implies that each adult brain stem cell is used only once and hence is disposable, as opposed to stem cells in the blood or gut that self-renew many times during the lifespan...But since adult brain stem cells seem to follow a 'use it and lose it' rule, does activating neuronal production too much exhaust the stem cell pool prematurely?"--Associate Professor Grigori Enikolopov, Ph.D., who led the CSHL team., Z0 @5 _; g# \7 a
' Z) }! q; r" v"Incoming students were voicing frustration that the existing PhD programs were outstanding within their narrow disciplines but none provided the cross-disciplinary training required for a successful career in regenerative medicine."--Theo Palmer, an associate professor of neurosurgery at Stanford University.7 j' X# d/ O, F9 f
H6 P$ \8 {) ~. _' K) E. i ^"We changed only one amino acid in normal tissue stem cells, trophoblast stem cells. While they maintained their self-renewal, these mutant stem cells had properties very similar to what people predict in cancer stem cells: they were highly mobile and highly invasive. No one has ever isolated a stem cell like that."-- Gary Johnson, PhD, professor and chair of pharmacology at UNC.
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"In this study, we looked at SOX2's role in cells of the peripheral nervous system and discovered that it's required to sustain multipotency – the ability to differentiate into several cell types in the peripheral nervous system, including neurons and glia."-- Dr. Terskikh, assistant professor in Sanford-Burnham's Del E. Webb Neuroscience, Aging and Stem Cell Research Center.
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This issue:
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Video news:
% G# @! U$ p+ H( nStem Cell Therapy Saves Woman’s Leg' ^' W9 u& p1 d
http://baltimore.cbslocal.com/20 ... y-saves-womans-leg/ |
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发表于 2011-5-15 19:54
木有这么久吧
发表于 2011-5-15 20:46
发表于 2011-5-16 15:36
