10岁女孩干细胞创建新生血管

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Stem Cells of 10-Year-Old Help Create Blood Vessel in Life-Saving Surgery
+ [1 ^' v& Y& X3 {9 gBy Rob Waters - May 10, 2011 2:00 AM GMT+0800
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+ E  O% \! L) }! J0 L- ^( f: HA researcher applies supplement to stem cells in a lab at the Gladstone Institute of Cardiovascular Disease in San Francisco. Photographer: Noah Berger/Bloomberg " H) e# i7 d) K) s
A 10-year-old girl with a deadly blood clot underwent a life-saving surgery that showed the power of using stem cells to regenerate healthy organs. 0 f6 O8 Y' r. Q1 w0 O" j5 k
The girl developed a clot in the blood vessel between her intestine and liver during her first year of life, creating the risk of potentially fatal bleeding. Michael Olausson, a surgeon at Sahlgrenska University Hospital at the University of Gothenburg took a blood vessel from a donor, chemically removed tissue and DNA from it, then seeded stem cells from the girl’s bone marrow to create a healthy, living blood vessel.
" L3 ~6 G- P. h1 p% {4 M“We carried out the surgery over three months ago now, and the result was very good, with no serious complications,” Olausson, of the hospital in Gothenburg, Sweden, said today in a statement. “The girl is in good health, and we believe that her prognosis is very good. Since the vessel was created with the girl’s own stem cells, she does not need to take drugs to prevent rejection.”
. d8 ~  p, a3 b/ C3 yA similar procedure was used in 2008 by surgeons in Barcelona to create a new windpipe for a 30-year-old woman whose airway collapsed from a tuberculosis infection. # Z' k6 C0 n* j  j4 t2 B
More research may lead to the ability to remake other organs and arteries, Olausson said. This might help patients who need kidney dialysis or surgery on arteries leading to their heart, Olausson said. 0 K0 R" v! C& o. b% {! @. j
While blood vessels from other parts of a patient’s body are sometimes used to repair such defects, liver failure can result if the vessels are inadequate, according to the hospital’s statement.
( V4 ^! p7 N3 l; k% p& WTo contact the reporter on this story: Rob Waters in San Francisco at rwaters5@bloomberg.net.
$ W# g7 G4 m; s, pTo contact the editor responsible for this story: Reg Gale at rgale5@bloomberg.net.
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zhangmingqi111

初次认领翻译，请多指教。( K* a" J, S  v2 U" x( P7 K
10岁女孩干细胞创建新生血管
  t! ?7 B) u3 \' s/ {一位有严重血管凝块的10岁女孩经历了一场由干细胞挽救生命的手术，手术展示了应用干细胞再生健康组织的潜能。4 j/ X7 k0 Z7 t, S7 ]' f5 i& m; }. j
随着女孩的不断长大，在她的肠子和肝脏间逐渐形成了血凝块，这造成致命的供血危机。哥德堡萨霍琳斯加大学附属医院的一名外科医生，Michael Olausson，他从捐献者身上分离血管，然后剔除血管中的多余组织和DNA，之后他将采自于女孩骨髓中的间质干细胞种植于血管支架上，制造了一个健康、有生命力的血管。/ b0 b+ y: Y7 q, {8 k
Olausson医生声明说：“我们在大约在三个月之前进行了这次手术，现在看来手术非常成功，并且没有严重的并发症。女孩现在很健康，我们相信她的预后也非常好。由于这个新生血管是由女孩自体干细胞构成的，所以女孩也不需要吃免疫排斥的药物”。5 i" j8 w4 w8 C$ b# ~5 E. f
2008年巴塞罗那曾经进行过相似的外科手术，他们为一位由结核病而导致呼吸道萎陷的30岁女性患者再造了一个新气管。
. S* M: _1 X3 }, S: Z+ L7 u- k/ X1 gOlausson说，更多的研究可以证明再造组织和动脉的能力。这项研究可能帮助那些需要肾透析和动脉手术的患者。
0 o& N: @! \* I) p2 V根据医院的声明，来自病人身体其它部位的血管有时用于修复组织缺陷，例如血管供血不足导致的肝损伤。