PDF：Statistical Bioinformatics For Biomedical and Life Science Researchers

lifescience1

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PREFACE
5 m2 N/ q& W( E9 nThis book has been constructed primarily as a textbook for a one- or two-semester( D' b8 m) \5 n0 \+ ~8 V
course in statistical bioinformatics. We hope that it will first serve as a comprehensive8 P5 ?4 B2 u1 J6 e) M$ y# A! E
introduction to a broad range of topics in this area for life science students and
) _: q4 \1 f- o) x0 y# Y, n' yresearchers who are motivated to learn statistical analysis concepts and techniques
+ Y/ z0 Y1 W. z8 b6 }7 H; uin bioinformatics. Statistical and quantitative science audiences who have not yet
7 g* A# v# f5 U8 h0 C) W4 }dealt with challenging statistical issues in recent information-rich biological and biomedical
' k, T5 j) w, h3 m9 f1 ndata analysis may also benefit from this book by efficiently reviewing the
/ ~; Y( u: N! Q: ]8 Mdifferent statistical concepts and techniques in such analyses. In particular, the four1 P/ P0 Z0 J- z9 e' B: G1 X
separate blocks in this book—statistical foundation, high-dimensional analysis,
  J: |: i) }) X+ h: nadvanced topics, and multigene systems analysis—can be somewhat independently
$ O, Y# j7 R8 X3 J* Nstudied and taught in a course based on relevant needs and time restrictions for an
3 @( P+ [: P( ?- O" I' s" u( Meffective learning purpose.- Z# k% Q6 J) @2 K6 k
A similar outline as organized in this book has been used for several years in a7 z6 I0 D2 I3 f& L8 G
one-semester graduate course which is open to students with diverse backgrounds at9 K3 C8 t/ Q( P' K
the University of Virginia. By publishing this book, we felt that these contents! C* @% _: D6 p( x' r$ x4 Y
could be significantly enhanced by direct contributions of more specialized experts
! L& {/ t" d/ A3 w4 b0 ]. Qin the broad field of bioinformatics. In this multiauthor book, we have yet tried to& ~& d+ _. [) B6 r
maintain the need of a high-level mathematical and statistical understanding at a minimum.
4 C7 h5 T9 U. f' y- T- P- CReaders of this book are thus assumed to have not much more than a basic college
$ a$ R3 I% q, Rcalculus level of mathematical understanding. A knowledge of matrix algebra: X5 y' b# u1 G9 ]
would also be useful but is not a prerequisite.
6 s8 f( i& D0 k" M& @This book is certainly a tribute to the contributions and support of many people./ ^: v% m6 |8 C* w- C. p% i, w% v
Acknowledgments are first due to the succeeding life science editors of JohnWiley &
5 i0 H( T" i) B. E; Y) T7 E  Y" h6 Y/ uSons: Luna Han, Thomas Moore, and Karen Chambers.Without their continuous support
2 c6 c/ }- z6 {8 tand encouragement, the publication of this book would not have been possible./ v, F# P% ]+ ?" z
Also, all the efforts made by the expert authors who were willing to participate in  W  B# V& S7 u9 m# Z( z
this book should be highly acknowledged for its successful completion. Finally, the
' I5 C8 T4 D# R1 o" L+ F) ]- ]( Kstudents who have taken this initial course and provided valuable feedback on various
4 E6 g' ]2 f4 P+ V" e' j) [topics in this area over the last several years are also significant contributors to the
; }! Z7 C* a& V+ ~% `& G, ]' `current form of the book. The preparation of this book was supported in part by the2 \1 S( C4 B$ n/ z$ z1 C" d" H
National Institutes of Health Research Grant R01 HL081690.
0 ]( R* @7 A- pJ. K. LEE. M/ N, @0 J2 V( E3 G
Division of Biostatistics and Epidemiology. M5 J+ a: [* S5 }; R% ~
Charlottesville, Virginia# |2 C; t1 R/ X3 y
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sunyucheng

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cjhpumc

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huangzhenbo131

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foxp3

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ibex

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ambassador

统计生物信息学！
3 d+ \% P" D& X2 H" y对于初学统计学分析概念的孩子们，这本书需要学习1~2个学期啊！加油吧！

jhmath

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hany2007

谢谢分享

hualin840518

Statistical Bioinformatics For Biomedical and Life Science Researchers