PDF电子书：Handbook of Human Immunology

lifescience1

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Handbook of Human Immunology" v5 E4 b/ S0 N4 E* C' X8 U1 V
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8 z$ j& s: c) ^8 @! [2 f2 OPreface
+ X9 U1 ?$ O. \4 I3 o5 USince the publication of the fi rst edition of the Handbook of Human Immunology in" s0 x8 ^& B/ N
1997, major scientifi c achievements have contributed directly to an increased understanding
+ s3 F  G5 P+ j$ k& Z. W' C" ?, Jof the complexities of the human immune system in health and disease.; L8 b" h- c7 f- F9 |! |
Whether directly as a result of the sequencing of the entire human genome or as a
( ]6 T3 }# R% lresult of the technological advancements in the completion of the latter, several new8 i" b( m# [& L* l- y# u
components of the immune system have been revealed, and new technologies for+ @7 k  {" D: b3 b/ B) Y* q
their measurement and evaluation have been developed. In the past decade, the number
* Y$ T7 D. j: }4 \( Sof recognized clusters of differentiation (CD) on the surface of leukocytes and
9 p. |( Q0 @5 U; e. b# zassociated cells has more than doubled; an entire new chemokine and chemokine# Y  @( h; z- a. D( U4 o
receptor nomenclature system has been established; the number of “lymphokines”# {  v) g3 I& u2 s1 ^" {  \
(now greater than 30) and humanized monoclonal antibody therapy have become a2 F* k# P7 q" s, N0 [( x
staple of our pharmacologic armamentarium (to mention only a few of the signifi -- n5 m. E7 U  y7 ]7 N3 m: z/ _4 M
cant immunological developments of the past decade). The discovery of all of these1 w' a2 L" ^$ v
immune system components has been accompanied by the development of new and
* [2 n( A' k+ Y5 x. fimproved methods for their detection as well as the recognition of the roles that these
- [6 j) j9 \# J# [. |! Gcomponents play in health and disease. These major breakthroughs are refl ected in( o/ W* }1 a& f; @0 D, @
the present edition of the Handbook of Human Immunology.
" q) f) i- |1 w' [9 j# X( m& ]' CThere are six new chapters for a total of 20 (compared to 14 in the previous
2 G$ e/ {% W# g' zedition) written by 12 new authors covering all the major components of the innate8 p8 p' N. P; N! r! N; L2 ]
and adaptive human immune system, descriptions of the specifi c human conditions9 Z' f5 o2 o4 k+ S
characterized by their assessment, the specifi c technologies and methods currently1 K) z, n5 I( }; r3 Z2 q7 S% ^
used for their measurement, and fi nally the relevance and potential pitfalls involved3 _  d! F$ ]* W8 Q
in the interpretation of their specifi c measurements.
% K' `3 x( i( H) p6 C4 fAs in the past, the book is introduced with an overview of the immune system," r/ ^+ f* v1 v6 n6 i3 D5 |
which is immediately followed by a new, practical, and fun-to-read chapter on “Statistics2 d% g" Q; Z9 ?$ R
of Immunological Testing” that is invaluable both in interpreting test results and also
0 I( H* @2 p4 {$ Iin the validation of new tests and the development of reference ranges. Throughout2 H) Z- L! [; L) I% S3 O/ e" H& q
this edition, readers will fi nd “normal ranges” including serum immunoglobulins,
1 y* d7 V- P9 v. B( O4 E3 kcomplement components, cytokines, and new to this edition—age-associated normal2 ?8 M4 E0 m' P$ T
ranges for lymphocyte subsets. The fi rst edition’s chapter on fl ow cytometry has been
) C9 n# g- ~; j7 Pexpanded into six completely revised chapters including a thorough treatise on general- _. Y5 a9 I9 x3 S: E5 h! d" d' x% j- H
fl ow cytometry principles and practice, quality control and theory, leukemia and lymphoma6 W  q( n) q! \! q$ N1 N9 p# }
immunophenotyping analyses along with cytogenetic abnormalities, an update
& c; s1 c7 w; g  P( G# e7 son CD4 measurement guidelines in HIV-infected persons and two new chapters covering0 e  G' p- j* C" y6 B
(1) the fl ow cytometry–based diagnosis of primary immunodefi ciency disease and/ b- \( Q2 t! e
(2) a history of the human leukocyte differentiation antigen workshops (now renamed
! N( E2 B' I, B8 M0 _$ N8 Pthe human cell differentiation antigen workshops) along with two comprehensive and
2 `6 @: c) i5 t5 Z; r/ every informative tables on CD.; C4 d. |3 p; @" |4 T( y
The chapters on clinical laboratory disease monitoring include laboratory methods3 N# Y9 O0 O! w1 }0 |- C8 D( `( C
for monitoring new biological therapies in the context of clinical trials and routine
( p$ \& p2 @3 [$ P) O8 c- I9 kpractice, an entire chapter devoted specifi cally to the immunological assessment o。。。。。。。。。。
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lifescience1

Preface' a. V$ g& ]4 R
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huangzhenbo131

It's a good book.

botizhou

Thanks.

zpzp0312

谢谢！~~~

ambassador

我原来就是考的免疫学方面的研究生~所以对这本书还是很感兴趣的！先下下来

llingzu

thanks

llingzu

xiexie

鸽儿

留着寒假里品味！

foxp3

good book