应用sandai virus诱导ips的文献

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Induced pluripotent stem cells (iPSC) have been generated from somatic cells by introducing reprogramming factors. Integration of foreign genes into the host genome is a technical hurdle for the clinical application. Here, we show that Sendai virus (SeV), an RNA virus and carries no risk of altering host genome, is an ef?cient solution for generating safe iPSC.

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7 L9 Z4 P3 L: R$ E学习学习，不过用病毒做诱导剂安全性还是令人担忧。