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本帖最后由 细胞海洋 于 2010-5-21 06:54 编辑 - d' n E$ v( K. {1 }7 k$ f5 p
+ b9 X; I" ~& u2 A% C% i6 d李凌松*，王 莉. V. J$ o* k1 G' ^7 a) z# G5 |6 l
（北京大学干细胞研究中心细胞生物学系，北京 100871）+ _5 J5 N& d: L/ v, \ ~
摘 要：胚胎干细胞具有自我复制并分化为人体各种功能细胞的潜能。胚胎干细胞具有的独特生物学
# b+ ?! k- Y' n特性使其被广泛应用于生物学研究的各个领域，特别是发育学。同时，它潜在的医学应用也成为世界
1 z1 Z, t h3 _/ E范围内的研究热点。但是，由于人胚胎干细胞的来源为植入前的早期胚胎，人胚胎干细胞自诞生之日
9 y5 w+ f$ v m) Z1 i. i起便倍受争议。本文将从胚胎干细胞的来源、特性、鉴定标准、增殖机理、应用前景以及研究本身& S1 i! @1 t; S) I) }" y/ T, Z
涉及的伦理学争论给予概述。, l* X7 e0 m" e2 q" t
关键词：胚胎干细胞；自我更新；分化；鉴定；胚胎生殖细胞；应用; c+ D, T( g9 y$ M. V3 a/ |
中图分类号：Q813 文献标识码：A; B- Q' p: I1 Q
Embryonic stem cells
7 J$ O. _* U/ `: [ qLI Ling-Song*, WANG Li
+ g$ M3 E* T7 d) O$ F$ q) S(Department of Cell Biology, Stem Cell Research Center, Peking University, Beijing 100871). G# a r9 j+ D# S
Abstract: Embryonic stem (ES) cells are able to self-renew and differentiate into all kinds of human cells. Due to- r6 S6 W5 r, K' k
their unique properties, ES cells are used in diverse fields of biological research，particular in developmental; J$ C1 R8 j" w% `2 G* V! e
biology. Meanwhile, their potential medical application become a research hot-spot worldwidly. Since preimplantation
1 b, u$ k% e% S. q! I% V+ H: O' A3 Yeggs are sources to generate ES cells, the use of embryonic stem cells is therefore controversial.1 z d& {7 E/ ], y6 g, z3 G/ O7 F
This review will outline characterization of ES cells, regulation of self-renewal, and the applications of the cell
4 `/ d# p5 a: A4 H$ E4 B( Qin treating diseases, as well as ethical issues related to human ES cells research.
: W( J: ?5 X. z( n9 CKey words: embryonic stem cells; self-renewal; differentiation; characterization; embryonic germ cells;) t: r; b+ s! p# A6 v# T
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发表于 2009-2-27 10:29
发表于 2009-7-14 15:44
