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本帖最后由 细胞海洋 于 2010-5-20 18:51 编辑
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* O: I8 b6 q' b0 c3 _4 C a3 }经典高引用次数专著,很多要用到microarray分析技术的朋友可以参看下。
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- D* `. P2 J) R$ w( F' Q4 O: c在拿到你的microarray数据后,不知道分析的话面对上百的上调/下调基因、microRNAs表达谱变化或target genes会傻眼的 - ]7 X. o, w6 D O" f
" c, l6 M; _# ?1 [Editorial Reviews
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"This book should be required reading for any (future and present) post-genomic researcher...": C( I# L6 {8 D' E- W" l
— Sean D. Mooney, Briefings in Bioinformatics
% H: y6 _0 _8 o0 e' l; sProduct Description, S N8 m+ e4 {3 z/ ]; ?
Functional genomics--the deconstruction of the genome to determine the biological function of genes and gene interactions--is one of the most fruitful new areas of biology. The growing use of DNA microarrays allows researchers to assess the expression of tens of thousands of genes at a time. This quantitative change has led to qualitative progress in our ability to understand regulatory processes at the cellular level. This book provides a systematic introduction to the use of DNA microarrays as an investigative tool for functional genomics. The presentation is appropriate for readers from biology or bioinformatics. After presenting a framework for the design of microarray-driven functional genomics experiments, the book discusses the foundations for analyzing microarray data sets, genomic data-mining, the creation of standardized nomenclature and data models, clinical applications of functional genomics research, and the future of functional genomics.; V6 h' ^4 O6 r1 k# }. M( p
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Product Details* `7 s7 b( ]" P* `/ H, p
Hardcover: 326 pages . v2 {. z0 h/ l# q' C" ^, z1 J
Publisher: The MIT Press; 1 edition (August 21, 2002) 4 O4 L9 w! o8 W' {
Language: English
( T5 F2 |0 r. c" G# OISBN-10: 026211271X
, Y$ X* |: }9 M- f& aISBN-13: 978-0262112710
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Introduction& C5 K& A( w' J" F. t( c
介绍请参见Amazon
6 q a7 q9 ?: f7 ^http://www.amazon.com/Microarray ... cular/dp/026211271X
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