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本帖最后由 细胞海洋 于 2010-5-20 18:51 编辑 5 P0 g% d. p) g+ m/ e+ u% z* p
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经典高引用次数专著，很多要用到microarray分析技术的朋友可以参看下。
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8 N/ O/ W% Q' y' u% f& ] T在拿到你的microarray数据后，不知道分析的话面对上百的上调/下调基因、microRNAs表达谱变化或target genes会傻眼的
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Editorial Reviews3 u# q0 n0 T( r! q- r5 @! y
Review8 X$ b9 f: s+ V; H0 N' k) i
"This book should be required reading for any (future and present) post-genomic researcher..."
( s7 o+ |! ]% X— Sean D. Mooney, Briefings in Bioinformatics 6 s; |. _* S" A% q) [8 N
Product Description
7 M7 f- n9 v9 C/ fFunctional genomics--the deconstruction of the genome to determine the biological function of genes and gene interactions--is one of the most fruitful new areas of biology. The growing use of DNA microarrays allows researchers to assess the expression of tens of thousands of genes at a time. This quantitative change has led to qualitative progress in our ability to understand regulatory processes at the cellular level. This book provides a systematic introduction to the use of DNA microarrays as an investigative tool for functional genomics. The presentation is appropriate for readers from biology or bioinformatics. After presenting a framework for the design of microarray-driven functional genomics experiments, the book discusses the foundations for analyzing microarray data sets, genomic data-mining, the creation of standardized nomenclature and data models, clinical applications of functional genomics research, and the future of functional genomics.) Y/ m' U4 J: _. R6 ~
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Product Details) B! D4 u; E0 x% ?+ O0 k7 L
Hardcover: 326 pages
- x/ b, I3 K+ D/ e5 H/ zPublisher: The MIT Press; 1 edition (August 21, 2002)
7 G% x9 N0 o/ i1 x8 U& \Language: English
) ], A2 I) r. a7 e3 D2 m! uISBN-10: 026211271X
! w3 c0 v3 N( |6 i) c1 uISBN-13: 978-0262112710
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% }0 \6 k. L7 w2 |; l$ JIntroduction* @ ^& V* f2 r o+ x+ k
介绍请参见Amazon( j: @) Z, O( Y
http://www.amazon.com/Microarray ... cular/dp/026211271X
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发表于 2010-5-20 18:48
发表于 2010-5-21 13:26
