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发表于 2019-1-8 21:46 |只看该作者 |正序浏览 |打印

"genetic mutation" should be exactly as "gene self-editing"
2017-12-1 13:177 v- w  u& x9 v
Bioreactor in vivo would be the terminator of illness.% N  S. M; I% V% [" v
2017-11-20 23:090 S7 k3 n, Z* _% L1 r/ |$ \
renew tech：剔除衰老（病变）细胞占位可以恢复青春。$ `/ C3 q$ y. _3 t) g9 k! z; x
2017-10-23 12:50
魔不疯，鬼不魅；道非盗，仙非妖；神无形，兽无极。
2017-9-30 10:58
Life 3.0——from decoding and coding to reading and writing" {) m' b8 i" F5 l* O* e4 L/ z4 ^
2017-9-21 22:328 _& J% L: s5 n1 Q! R" ]& F
理论创新：亮明立场——先颠覆，再完善& E! ?  A$ ?3 [9 @( t
2017-2-7 00:07$ f3 n/ D6 i; d) V6 K' z
干细胞第二定律：与细胞外基质共同构成多潜能；2 i  ~. l1 [( h8 c. E9 J
2017-1-3 11:14
干细胞第一定律：全生命周期保持增殖分化能力；
2017-1-3 11:13# N7 T  {" b' I
NgAgo——Never give A guideline operated！
2016-12-1 10:09+ A& c8 i% K3 ^& r, ~
表观遗传—— 一切皆可改变  一切皆有可能% y8 o2 g( J% s5 X/ V3 o1 o
2016-8-17 23:370 i/ Y# l5 v9 c6 L1 D* v+ P
子曰：吸血鬼疗法——养儿防病养孙防老. g; |, F+ g% ]$ u1 }! D0 m7 J' T
2016-5-23 12:056 m/ I. p! e0 P* J5 ^
NgAgo——Debug tool kit for mammal cells
2016-5-9 13:09% n& c- `' F# c; C- Z- t, J
公理之外皆需证明；科学命题皆可证伪。7 D3 H2 j1 v" U; ^, R
2016-1-2 00:20! c2 b/ f) \+ R  Q+ n/ B
低氧——破坏线粒体功能、诱发炎症、导致基因突变( X* [; J' y& P
2015-12-16 20:191 u$ J& q. E9 }7 _2 Y9 h
癌症——炎症部位组织再生过程中细胞去分化失控形成的幼稚化新生物。+ v( D, r7 k+ h+ L
hcoohboy: 一个有趣的假设~但是没有炎症就一定没有癌症吗？ (12-18 16:16)7 I% k7 @% }9 ?
sunsong7: 炎症与癌症同在，Hanahan D, Weinberg R A. Hallmarks of cancer: the next generation[J]. cell, 2011, 144(5): 646-674. (12-19 19:45)  K# M# ?+ h8 c2 E
hcoohboy: 3ks~ (12-24 16:45)  ?) g! B* L5 R! m" i9 o9 c
2015-11-18 15:54
抽象世界与客观世界的真理判别标准是不同的：在虚拟数学世界里，逻辑是一切命题的唯一审判标准；在客观物质世界里，证伪是一切定律的最终审判依据。8 j, P7 K6 M: N
2015-5-20 14:13
传统生物学将死：进化论=自然神论基因轮=宿命论细胞论=活力论翻版。现代生物学曙光乍现：系统生物学=数学结构生物学=物理学合成生物学=工程学1 k" Y- J. F; c# S$ G, p
helong: 系统生物学是把细胞、基因、进化、物理学、信息学（数学）、工程学等都打包起来的所谓新学科，目前只做到了简单组合，还没有达到系统集成阶段。合成学更多偏向于化学。 (4-21 19:28); K; m% r3 d# K$ `9 \! E6 ~; g5 v
sunsong7: 方向对头，努力总会有结果的 (4-21 20:05)4 B- d( [, f+ L- X0 S+ J% S
2015-4-21 16:46
search and research is just disassembling the creature.
2015-4-7 17:01. d8 E( S: j# \+ U7 F7 E
selection is  the act of intelligence
2015-4-7 13:49, @' D2 [6 ^0 \7 o8 z7 u5 h- |
Genome fusion create neoplasm9 G1 p8 O$ l3 {, S& B# W
2015-1-20 13:105 b( Z0 y+ `, n5 I, O, B5 e0 ^# A
STAP——Stupid Trick  Against Professional / Z! l: `8 n0 s) c' S6 h
2015-1-1 19:29- o( D) t: H* Q7 f9 G* t+ K
information=structure=negentropy
2014-7-22 17:36; S7 ]' i, p* K& Z& }! j! s
Natural mutation does not result in new functional genes
2014-7-3 14:06
life is wisdom creation instead of natural evolution
2014-3-27 09:339 ]2 q8 ~# ?  u/ R
let us explore the source code of life !
2014-3-11 13:11
bio-manufacturing——processing，machining，casting，printing，3D prototyping，duplicating，cloning，life replicating.
2013-10-7 23:06
induced abortion would give the key for curing cancer . ~7 f" S2 n& V: |
2013-10-2 23:33, F8 O2 ]. I, g* s' {7 ~
“key breakthrough” in molecular biology are entertainments$ B% |/ Q" t6 H% i
2013-6-16 11:50
Rules Of Living：trial-and-error exploring，survival takes the legitimacy
2013-6-16 11:27
Life is a set of debuging programs! J+ b6 K$ J! J' X' ?
2013-6-15 18:40
current biology is closed，destined and agnostic，it is  the only contribution is to kill cells0 }- s& ~- p5 g7 P  R& C: Z
2013-5-2 08:54
information，energy and construction are the new base stone of biology，instead of evolution，gene and  cell  tales6 E& o# i& W& s) y
2013-5-2 00:51
virus is the messager of  the universal life network
2013-4-18 14:33% N% s- j" S, |, ~6 H
Genetic information doesn't improve cancer risk prediction0 q3 H$ t1 f; w  p0 ^
2013-4-1 09:20
There is no early diagnosis of cancer，but early prevention of it
2013-3-27 09:17$ g# X$ L4 t& Z# S* P7 @
hypoxia maintains stemness or carcinogenicity
2013-1-2 05:21) N' q( ?( Q9 P5 \( v
cancer is the living fossil records on origin and evolution of human being2 B7 x4 {2 S* R' }: d
2012-12-9 23:31
information island results cancer6 O3 \1 d( p+ a1 ?! a1 |1 ~7 E! M9 {
2012-12-9 05:230 b# A- u- [# i7 n$ B/ a- Q6 `+ ^/ x
life is digital game- J  L. s- i4 P- ?+ m
2012-11-10 00:17
cancer ——severe abstinence reaction of cells to niche addiction2 ^+ a0 i2 M  W, h6 d2 u2 o/ W* U
2012-9-28 12:115 d8 \. I5 E- E8 S1 l. r
未来生物学终将回归物理(熵)及数学(分形)的美感2 J2 B) C# V5 a; F0 ^
biomater: 熵理论适用于任务物质。。。。也适合于生命 (9-26 09:28)( T1 S+ p$ r$ @8 z+ z, N) V: {5 M3 G
2012-9-25 21:22
membrane holds the key to life
2012-8-19 20:24
Cancer is the default state of cells: ~* d5 Y) [0 Y$ a( p2 Q
2012-6-26 22:177 p7 X! u' n6 n  T
mainstream cancer theories could be overthrown！, n5 d8 j% B" F4 q5 r6 R5 D
2012-6-25 15:439 ^: ]; s* |. S
carcinogenesis has nothing to do with the gene mutations but is  the result of niche reprogramming...7 |! k& l. a& ]. I0 V6 G  e/ M
2012-6-7 09:36+ j9 o8 P% M# T$ Z9 e0 a
every living organism connected with the water， one cell one world0 p- Y" p; ?$ m/ }
2012-4-19 22:06
chemical structure of cancer cell determines it's biological function...
2012-4-7 17:56
Mann tracht und Gott lacht) u) m# r/ H, ~5 X. N
2012-3-24 21:34: P6 `  X) O% N! z
Darwinism or genetic determinism is a fairy tale！
2012-3-13 15:186 L; b, H. e# q* }' `
niche isolation is essential for cancer speciation3 A9 c  D9 e  J: s" D7 _
2012-3-12 12:07+ ]. x% x+ o* i5 e% O: v
Hybridization Creates New Species，Mutation results species extinction
2012-3-11 18:21
ROCK may join the niche reprogramming...' D* `# R$ e. U5 H
yuhaoze: 这是篇文献吗？ (3-9 10:41); ~; K& b4 O7 X7 ^1 I
sunsong7: http://www.stemcell8.cn/home-space-uid-6268-do-blog-id-1211.html 突破：病人体细胞及肿瘤细胞长期体外培养（附原文） http://www.stemcell8.cn/thread-51419-1-1.html (3-9 10:46)
yuhaoze: 啊，我看过这篇，还顶了呢，谢谢哈 (3-9 14:37); {) L1 |# z, d% s( h7 j0 T
2012-1-19 10:52
oncogenes are pseudoscience0 s! b, c! X& P% N( `
2011-12-29 13:55# B% l6 [) b8 B0 m0 t7 v
gene mutation leads to variation or extinction, not new species
2011-12-29 13:28) g6 D! `3 N' u: J! v
oncogenesis is non-Darwinian event
2011-12-28 22:561 G* L9 E- @4 M9 h+ h: m9 J; M# D% q+ W
disorganization activate neurogenesis activate oncogenesis
2011-12-22 23:38. h4 s$ [2 h) C" _) [5 \* s$ V
MSC is cell feeder，tissue scaffold，immune firewall and biological glue
2011-12-19 19:46
cancer is Noah's Ark（species carrier and life explorer）7 b4 w( f& p+ y  o5 h
2011-12-10 09:465 g7 v$ `. F% C
cell fusion create new species, gene mutation induce variation" W' k6 H4 a( s6 s
2011-12-10 09:36( ?3 H- u( G5 i- t3 @0 z' `* t1 `2 I! q
GVT will be cancer terminator， Cytokine storm will be cancer preventor
2011-12-8 12:56* C+ h! [- T( g+ W" n
cell fusion results regeneration，reprogramming，neogenesis，atavism； cell division results differentiation，apoptosis，senescense，development;7 g& P# @$ F6 S0 N: r: t
2011-11-27 14:547 h6 N1 n* H& e3 t0 |1 Y
Cancer is between protozoa and mesozoa， not metazoa...! A) Y1 W. p+ v0 Q! m! d
2011-11-27 00:25
cancer is neurological disease！ haha，I got it！9 i' ]' Q) U3 _5 c. a
2011-11-22 22:06- \4 X' r8 j0 N  F1 _
you are cancer，fetus is tumor. 佛曰：汝既是癌癌胚如来
2011-11-12 11:27+ x; x2 r2 x  U- `: l+ Q
cancer is the ecological invasion of hacker...
2011-10-5 10:317 F# W  v) `1 s% D7 x
microRNA is  negentropy？
2011-9-24 00:48: ~) j8 [/ ~' K2 Z7 o; K
cancer is the social problem
2011-9-9 23:338 h& \2 i1 x6 ?/ p  a% u2 \2 J0 A( D8 M
Science is the games of nobleman or madman
2011-9-2 15:03
cancer resulted from disturbance of biological liquid crystalline state of ECM
2011-9-1 20:13
niche n-dimensions——space, time, momentum and entropy; energy, material and information flows; physical, chemical and biological factors；topological, thermal, and fractal influences...
2011-8-13 00:37( s: p1 x% {$ F
Second recession is coming？  O4 g" f4 m9 o4 j
2011-8-9 23:58) Y+ W1 m5 |2 ^3 v% N) a
cancer may be from sexual reproduction of somatic cells.6 ~- u( ^1 r- |1 z, y8 L
2011-8-7 00:16
who determine gene？ genetic determinism is fatalism！2 F0 O) J, D" z+ o6 i
2011-7-30 11:26
niche reprogrammabllity is the key of solving cancer problems...
songtianlong: i can't agree more!!!O(∩_∩)O~ (8-14 20:42); q+ ]; V/ w# j0 T" d7 R, ?
sunsong7: hehe. thanks for interested in this topic, welcome future discussing (8-14 20:54)
2011-7-24 01:24( e& a1 w3 L: M0 {8 Q
cancer results from acquired genetics alterations.# Y0 ?( A/ A6 o+ w, |- b- J
2011-7-20 21:37
CSCs are the low differentiated cancer cells in G0
2011-6-29 16:30
iPS future——in vivo direct reprogramming ...  |5 Q) t. B& q+ x' H; M
2011-5-31 15:20. }0 J- Q6 c7 a9 I" R# h3 H
niche reprogramming——cell fate will be manipulated by cytoplasm - microenvironment interaction http://www.stemcell8.cn/thread-40755-1-1.html
2011-5-31 01:28
all the somatic cells of Mammals are totipotent ！
2011-5-22 22:22
miRNA——The manipulator of  cell fate！
2011-5-20 20:21. {6 l8 y) N5 ~7 I4 H& \& Z# W# n; }0 X
《Cell Stem Cell》means “cell is stem cell” 活细胞就是干细胞？, l6 e$ W( F+ W/ _( @# J7 ^
2011-5-17 12:38
cancer —— good nuclear in bad cytoplasm！RNAs are cytoplasmic determinants determine  cytoplasm determine cell fate！ division is differentiation is cancerous is life ！# {- q0 W- K+ Y0 p- A2 g  I4 `
2011-5-11 12:31
cancer results from cell dedifferentiation...; b- Y' l% p! H% p; x
2011-4-28 18:07
differentiation——asymmetric cell division ！
2011-4-28 18:042 c. L1 Z/ @/ |; ]9 c' N6 L; H4 @
cancer origins from the regenerative cells！
2011-4-28 17:52! Q: r% x5 N( m! O2 i
Proliferation is differentiation potentiality！+ p1 r! v& b3 c" p+ `* _* F
2011-4-28 17:49
iPS——the key of Pandora box！
2011-4-27 22:36' m6 [1 u( {- h- I- s# t5 b, ~/ i
Aristotle— "The whole is greater than the sum of its parts.", z  J# \# W- E; E
2011-4-27 00:20
cancer——atavistic cells
2011-4-20 00:20! J; z+ j& d0 y. }
cancer——cellular atavism！
2011-4-20 00:18( ?0 c2 Q; ~! C# \
cancer——evolutionary ancestors of mammals./ v. X) g6 K7 o0 q+ _& p
2011-4-20 00:09% u6 l0 ?/ B! R8 |  q3 g. z
肿瘤是细胞自组织缺陷的产物 6 X: ], w) w) q/ T8 |9 t
2011-4-17 01:41
cancer——Metazoa 1.0
2011-4-17 01:00% U, O6 ^. R$ c5 K! G, l  P8 _
US——the Axis of Evil！
2011-4-4 01:19
美国是世界的邪恶轴心！0 `( ^, G' x, ?% M% A6 q0 H4 s
sunsong7: 沁园春.血            ---作者：萨达姆   日本风光, 千里地震, 万里海啸。望仙台内外, 废墟莽莽；东京上下，顿时逃逃。核站爆炸，世界惊涛，地震海啸试比高 ... (3-22 21:25)+ [: N) R9 N. f# t
2011-3-22 19:06) {9 {  h8 l  E6 U
teratoma is derived from endogenous iPS！
2011-3-15 21:44
ips is a luxury gambol on  + O0 z0 j! H) B; R
2011-3-3 14:50
cancer is intermediate of species evolution
2011-2-12 12:29: e0 U% R  l% A1 }) R
stem cell now is on the eve of coming medical revolution
2011-2-12 11:20& M4 g" E, P! _
Inflamation is the reprogramming process of somatic cell in vivo！
2011-1-31 14:49
so-called medicine is niche regulator！
2011-1-23 21:458 }/ f4 D5 x" c3 J% P4 D
endogenous iPS is the cancer initiating cell！
2011-1-17 16:47* H- }4 O: Z& z  f
cancer is unicellular organisms！
2011-1-9 22:04) A3 z- z6 e5 `4 i
Pandorabox Has Been Opened8 `) I* N) E4 a+ Y2 o" e
2011-1-7 23:24* N& w9 f0 O  i" D/ B! |/ {( ~
iPS is the Emperor's New Suit ! 9 |( F' b6 O8 r1 u- F
2011-1-5 23:50( C! K4 X& \+ o& K
cell-free is the final solution of stem cell therapy8 g+ y* e9 a" I. C) R1 D6 Q
2011-1-5 21:46! H5 X1 [; M* N
niche is telling the story of stem cell.../ W0 |* s# e8 u
2010-12-29 17:327 l. Z) L; ?. O9 {0 a7 _: N
cancer results from reprogramming of somatic cells: H0 _  w: q% ]- t
2010-12-25 18:56! b5 Q2 Z2 P6 \2 L( L
cancer——good cells in bad niche！9 J# f, N" J* m3 V: B* x
2010-12-25 16:02
cancer无罪——制造产生罪犯的土壤才是真正的犯罪！
deron: 灰常同意，有相关文献么？ (12-19 09:41)
sunsong7: 呵呵，请来参加讨论——癌细胞的发生可能是一种“返祖”现象？ http://www.stemcell8.cn/thread-32073-1-1.html (12-19 11:33)/ w1 N5 c. @; i
sunsong7: 问题讨论 http://www.stemcell8.cn/forum-re ... 709-pid-246202.html (12-19 13:29): N1 C0 W6 r' P* w7 u6 {
2010-12-18 15:54; d1 x' n' l1 O# H
子曰：上善若水大成若缺——干细胞治疗的终极解决方案将是不移植外源干细胞！
2010-12-15 15:070 u( B' C& O0 _6 J2 ~
老狼的记忆——大洪水
2010-12-13 23:25) V/ I; f( |) x* K) D1 w2 K! H
can cancer randomly differentiate into norml cell in vivo
2010-12-13 22:33& q1 t3 A8 N1 ?' G! {( e4 ^' h6 H
omnis cellula e cellula
2010-12-12 09:28
Stem Cell ——The Origin of Disease8 L* n) u7 U1 F" [) ~  m. n
2010-12-12 09:27

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