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发表于 2019-1-8 21:46 |显示全部帖子
"genetic mutation" should be exactly as "gene self-editing"
' f6 t, |5 M: d/ [2017-12-1 13:17/ c2 M4 l0 K1 L8 l9 f4 Z
Bioreactor in vivo would be the terminator of illness.
# n; ?1 _$ B) ]5 s* D7 T. k9 w2017-11-20 23:09
( N* e) T5 E3 Y; Y# G% z6 I. C6 Krenew tech:剔除衰老(病变)细胞占位可以恢复青春。
4 d, j1 o/ F: k" |7 j6 e& L! Z3 w2017-10-23 12:50
4 `; |/ e, e. U' U; `! G2 C7 S魔不疯,鬼不魅; 道非盗,仙非妖;神无形,兽无极。
1 B) d3 @' ^* n5 M7 \1 h2017-9-30 10:58
& _, [. H, z: m/ s0 S9 e. _! uLife 3.0——from decoding and coding to reading and writing* U" M! q* O6 N9 X0 v. [
2017-9-21 22:329 I7 c# K9 E0 }7 D1 u1 e
理论创新:亮明立场——先颠覆,再完善* k# A# ~/ x6 C; N* M# C
2017-2-7 00:07
4 P2 o$ }! \  V3 i+ H. |/ j2 A! H干细胞第二定律:与细胞外基质共同构成多潜能;
: t  ]4 x* g7 v7 K, ?% n2017-1-3 11:14
6 m. V! t' r/ ?2 r/ W% @  g. n干细胞第一定律:全生命周期保持增殖分化能力;
# G3 Z, t( P. _2017-1-3 11:13
% K0 @$ e% @' m0 vNgAgo——Never give A guideline operated!
( T! h& n$ `. B% h5 g# {  d2016-12-1 10:09
, O. [% t, v1 D表观遗传—— 一切皆可改变  一切皆有可能& z! ]5 [1 I& x8 [* O7 R# }9 L$ k
2016-8-17 23:37+ |' z: `! y' d0 w; O' _
子曰:吸血鬼疗法——养儿防病 养孙防老* ~) {( S; n8 O* J! a
2016-5-23 12:05
$ M8 t) @0 n+ e, wNgAgo——Debug tool kit for mammal cells( _  T) B6 G, h9 T% @
2016-5-9 13:09* C  E1 \; [- T; w  t: j& h
公理之外 皆需证明; 科学命题 皆可证伪。& p* ?1 `; y/ u# s
2016-1-2 00:20+ I) m) T5 R6 F  ^; H2 M
低氧——破坏线粒体功能、诱发炎症、导致基因突变# ]! y2 o  U% w  a6 S0 U+ H
2015-12-16 20:19
/ W4 [9 m. a6 F9 a( S癌症——炎症部位组织再生过程中细胞去分化失控形成的幼稚化新生物。2 [4 T3 Z7 G) I$ n& f
hcoohboy: 一个有趣的假设~但是没有炎症就一定没有癌症吗? (12-18 16:16): w' r7 k) k4 c+ l4 G  y0 n8 W) g
sunsong7: 炎症与癌症同在,Hanahan D, Weinberg R A. Hallmarks of cancer: the next generation[J]. cell, 2011, 144(5): 646-674. (12-19 19:45)
5 Z7 }  `" {6 h3 v- D1 B3 m, dhcoohboy: 3ks~ (12-24 16:45)9 I5 _1 V( f; L  Q9 O2 E
2015-11-18 15:546 p) {3 v- a# M0 ^/ i
抽象世界与客观世界的真理判别标准是不同的: 在虚拟数学世界里,逻辑是一切命题的唯一审判标准; 在客观物质世界里,证伪是一切定律的最终审判依据。
5 `8 x7 d7 [8 q2015-5-20 14:13, v# q+ K2 E& x2 q, b8 C# e
传统生物学将死:进化论=自然神论   基因轮=宿命论   细胞论=活力论翻版。    现代生物学曙光乍现:系统生物学=数学 结构生物学=物理学 合成生物学=工程学
/ ?, p* E$ q; |, E$ dhelong: 系统生物学是把细胞、基因、进化、物理学、信息学(数学)、工程学等都打包起来的所谓新学科,目前只做到了简单组合,还没有达到系统集成阶段。合成学更多偏向于化学。 (4-21 19:28); m# x1 Q! z$ L# U) I2 m0 s4 ^% S
sunsong7: 方向对头,努力总会有结果的 (4-21 20:05)
0 X$ a9 \! S; J2015-4-21 16:46$ i  x1 Y6 H2 X& u9 H* L* E  s
search and research is just disassembling the creature.( j' n% @0 F) h- u% i
2015-4-7 17:01$ U4 c' D& \" o/ Q
selection is  the act of intelligence6 F/ u5 ]* ]# Y% n  B  k' r
2015-4-7 13:499 V5 s0 X; q  n3 m- K7 @
Genome fusion create neoplasm6 p( r4 @3 I8 y# |4 s! c
2015-1-20 13:10- x5 N# {' z0 H; N% n2 R/ t1 u* r/ i
STAP——Stupid Trick  Against Professional 2 ~: L& T$ A8 D, f
2015-1-1 19:29
6 h  m/ l1 T& c9 b2 X' [  _7 ainformation=structure=negentropy
/ G% C# Y0 |( F0 l9 X, D4 h! B6 Y5 E2014-7-22 17:36
3 }% b) W- v+ l. H" J. SNatural mutation does not result in new functional genes 
. L( ~2 y4 a& x. y2014-7-3 14:068 A5 i8 N9 o! l2 Q/ w" Y8 N
life is wisdom creation instead of natural evolution' m4 g% Z  v2 X  K3 ]  ?2 ^6 y
2014-3-27 09:33- H1 r) i; f6 _- i
let us explore the source code of life !1 n1 C9 F/ S& t8 X
2014-3-11 13:11
4 }, l  ]9 \" Pbio-manufacturing——processing,machining,casting,printing,3D prototyping,duplicating,cloning,life replicating.
1 L, z- @* O& y. A2013-10-7 23:06% N; C1 m5 a- F8 |2 M; b
induced abortion would give the key for curing cancer 
) L# a( k$ o: {: J3 \% s  K2013-10-2 23:334 Q4 {3 R" j, D) K) x% j' @
“key breakthrough” in molecular biology are entertainments
4 p( m1 g" `) g$ @" N8 M2013-6-16 11:50
$ d: Y+ c/ N( ?! E9 ?( U: C: d  fRules Of Living:trial-and-error exploring,survival takes the legitimacy
. E+ j2 R5 D- u# s  @7 v2013-6-16 11:27; E5 v3 {& e3 E+ c% C* ^9 c
Life is a set of debuging programs; z5 {9 M) U3 z9 s& @4 a$ |
2013-6-15 18:40& Y3 L( h. F) n# w+ G6 J" @/ t* s
current biology is closed,destined and agnostic,it is  the only contribution is to kill cells/ ?2 D; M5 K+ G: k  \- @( @# C
2013-5-2 08:549 `& B/ ~  ^: M4 ~& O- s
information,energy and construction are the new base stone of biology,instead of evolution,gene and  cell  tales. K; J" g9 D: U2 b! M* d) e
2013-5-2 00:51, n; `" G, g5 W2 Y
virus is the messager of  the universal life network# z& p. L2 l5 C7 S; k1 o: C. f5 @/ S
2013-4-18 14:33: A+ t9 Q) }( h7 k( ?
Genetic information doesn't improve cancer risk prediction4 K2 A6 Q: a; ^
2013-4-1 09:20) b- U9 w# I2 ?6 Q" y4 q
There is no early diagnosis of cancer,but early prevention of it# u* V& U/ R8 ^: q' c2 O; R2 B- t5 v
2013-3-27 09:17
  a% A" M$ ]  ?hypoxia maintains stemness or carcinogenicity! H" T' V9 n- z: r
2013-1-2 05:21
! K! M  G9 L0 J, K6 {+ K  Y" T" r4 g: V4 Ccancer is the living fossil records on origin and evolution of human being( @! n# A$ I+ P2 r
2012-12-9 23:31
. G/ i0 R. |& W; Z. F; i! e7 q+ dinformation island results cancer" ^/ I, p" N9 L$ T( \4 Q
2012-12-9 05:23; |: I. {$ u4 e6 w& ^
life is digital game
; o, S! L' s( q4 C. L; Y; q1 l2 z8 o% [2012-11-10 00:17' V6 i" K2 B$ `% l9 s
cancer ——severe abstinence reaction of cells to niche addiction
0 d$ ]" G% g1 i/ J- o2012-9-28 12:11, c! Q" U; [% _& v( n" X
未来生物学终将回归物理(熵)及数学(分形)的美感! X3 u  x% ^' d: J2 ~) o
biomater: 熵理论适用于任务物质。。。。也适合于生命 (9-26 09:28)0 O/ k2 c! S7 j+ A0 w, }
2012-9-25 21:22
$ x' G: F! q; I/ d4 mmembrane holds the key to life
" S: _% @* f4 \2012-8-19 20:24  i4 k( x( `2 e( s
Cancer is the default state of cells
2 {3 V5 s$ j4 G8 `0 D2012-6-26 22:17
7 L) |* M! K" g# @mainstream cancer theories could be overthrown!
5 f' `# ~3 C0 h8 y2 X0 t2012-6-25 15:43. w+ @& s: G8 M# Y% M( ^
carcinogenesis has nothing to do with the gene mutations but is  the result of niche reprogramming...
- Z- G) {2 ^7 j! c' b! n! c$ W2012-6-7 09:36  i/ \, V( G% k/ w7 ]" v
every living organism connected with the water, one cell one world
2 v% t. t% @& C, r5 o2012-4-19 22:06
4 D' ?# C) E7 u, T' m. ]! k! gchemical structure of cancer cell determines it's biological function..., ^% X5 \- B( e5 p1 i, y9 {
2012-4-7 17:56* i4 c/ f' S, w
Mann tracht und Gott lacht0 ?$ h( P0 v( }' x/ y7 G! ^7 g4 S
2012-3-24 21:343 M0 D! m7 F) M2 \
Darwinism or genetic determinism is a fairy tale!' r; [1 g5 x. v& {+ k' z
2012-3-13 15:18- X, x) r$ w% G& c4 n
niche isolation is essential for cancer speciation- B  M9 f" ]' h! T
2012-3-12 12:07/ \0 l8 V$ p2 A
Hybridization Creates New Species,Mutation results species extinction
8 V: K0 |8 T, z2012-3-11 18:21- C- p, i3 W  v4 s% \6 B
ROCK may join the niche reprogramming...5 M. n. F+ g6 M/ I6 C6 M
yuhaoze: 这是篇文献吗? (3-9 10:41). m7 Q- [+ P, i7 `; q% h
sunsong7: http://www.stemcell8.cn/home-space-uid-6268-do-blog-id-1211.html 突破:病人体细胞及肿瘤细胞长期体外培养(附原文) http://www.stemcell8.cn/thread-51419-1-1.html (3-9 10:46)
& p) J) x! _+ R' Syuhaoze: 啊, 我看过这篇,还顶了呢,谢谢哈 (3-9 14:37)
3 y; L  I; M1 w+ |& J2012-1-19 10:523 f8 g2 a  ^+ k/ h  {2 @
oncogenes are pseudoscience
, |, U& P+ M4 v, ~8 {) N  u& x- R2011-12-29 13:55
* K+ [2 R6 m, c/ Ngene mutation leads to variation or extinction, not new species
" y2 t# @, m- g2011-12-29 13:28& k  C# f7 Y- x' l/ r$ v
oncogenesis is non-Darwinian event( O, \+ P4 [0 b5 W
2011-12-28 22:565 R( c  y& x# j" L
disorganization activate neurogenesis activate oncogenesis   
  w8 k. T7 I0 S* W" W6 k/ I2011-12-22 23:38
( P& ^+ i$ b, g! m# jMSC is cell feeder,tissue scaffold,immune firewall and biological glue# c9 f& p% Q# U0 s5 v. T$ G5 X3 I
2011-12-19 19:46. Q0 R4 z; ]. `$ j$ u7 Z0 k+ c0 S
cancer is Noah's Ark(species carrier and life explorer)
' P$ T& U) d  j  Q) [( _2011-12-10 09:46
. S3 q1 F* l& ycell fusion create new species, gene mutation induce variation
- U6 s5 z' H4 Z7 l+ A! E2011-12-10 09:365 D0 ]. I+ ], G" U) v
GVT will be cancer terminator, Cytokine storm will be cancer preventor
0 f: Q& u! M3 i- H$ b2011-12-8 12:56! ^4 ^* b/ f, t0 e
cell fusion results regeneration,reprogramming,neogenesis,atavism; cell division results differentiation,apoptosis,senescense,development;9 D; _: w( ]1 F) n4 y( g
2011-11-27 14:54/ V9 e" E% m$ T- S/ r  N5 A
Cancer is between protozoa and mesozoa, not metazoa...) s9 X! j4 v# N; E8 Y
2011-11-27 00:25+ x0 t# j4 ?& t
cancer is neurological disease! haha,I got it!
% p  r7 \- X6 K- L2011-11-22 22:06
. `: J) N: Q' k5 {! |you are cancer,fetus is tumor. 佛曰:汝既是癌 癌胚如来; E  n6 B2 Z# d# V7 N1 S! G: Q
2011-11-12 11:27
- I( Z1 R! @+ W0 u) n: `$ Hcancer is the ecological invasion of hacker..." n. O* S( b- q  |* c
2011-10-5 10:31: k0 _1 Y9 t2 H, z/ k
microRNA is  negentropy?  `9 O: v/ `' {7 {$ y
2011-9-24 00:48
8 K1 P; O# |- p3 q8 y; M% h7 pcancer is the social problem* j  Z+ t- X. f+ u+ ~
2011-9-9 23:33/ _4 z; p) L5 l/ Q
Science is the games of nobleman or madman9 k' t! T; p$ S/ N. S$ J3 z" D1 @( J
2011-9-2 15:03
2 s& u( d$ ?* t4 n) ycancer resulted from disturbance of biological liquid crystalline state of ECM: u) W1 m. T+ Q/ z6 C2 A+ i5 T
2011-9-1 20:13% b6 H5 ?" ~9 f) S3 `! {
niche n-dimensions——space, time, momentum and entropy; energy, material and information flows; physical, chemical and biological factors;topological, thermal, and fractal influences...
/ E3 p4 y  M9 Q+ _" w, D2011-8-13 00:37, m# P7 ^6 K) h
Second recession is coming?
0 U2 R- E; Y+ k: Q7 x2011-8-9 23:58
( B, U0 |" [4 k; dcancer may be from sexual reproduction of somatic cells.
; d( I6 L! F7 n& r7 x" x( z2011-8-7 00:16
; b) B7 Y3 r7 |- d+ @1 c2 o+ Bwho determine gene? genetic determinism is fatalism!
9 s2 |! J2 v$ A" r4 w2011-7-30 11:261 c' l6 J) [4 a8 F: @! I  {* W
niche reprogrammabllity is the key of solving cancer problems...
; x6 x3 \! h, V8 x% n/ H" D' Y/ Ysongtianlong: i can't agree more!!!O(∩_∩)O~ (8-14 20:42)
) q3 e& A1 F7 m! ?9 Q# Qsunsong7: hehe. thanks for interested in this topic, welcome future discussing (8-14 20:54)
, o6 r- a) V' d; v( \1 l2011-7-24 01:24" k1 ~  n: U: }: A) n( o. J
cancer results from acquired genetics alterations.8 _* z  i5 |( ]
2011-7-20 21:370 b  o  K+ O0 s8 h" P* _
CSCs are the low differentiated cancer cells in G0
: C6 w5 w: _* W3 C% l2011-6-29 16:30
. _6 M) s# ^' l  g* }iPS future——in vivo direct reprogramming ...
3 |9 P" Z7 I% m, M% g/ |7 a2011-5-31 15:20
' N1 g0 y2 a3 w! mniche reprogramming——cell fate will be manipulated by cytoplasm - microenvironment interaction http://www.stemcell8.cn/thread-40755-1-1.html7 ^8 _  e6 }2 M8 q5 I, E7 H
2011-5-31 01:28
0 \) ]6 q5 D) w$ Hall the somatic cells of Mammals are totipotent !
/ N' R7 Z& F8 s: g/ C; l# |, k$ h. F2011-5-22 22:22
/ H, ]; m  A* v7 dmiRNA——The manipulator of  cell fate!
! y- w6 V5 i6 C6 Y8 D6 R% C* |3 n2011-5-20 20:21
0 n% A1 d3 V( f# c% I* w" g/ H《Cell Stem Cell》means “cell is stem cell”   活细胞就是干细胞?
* K! ^" R6 ~1 U+ [. C2011-5-17 12:38
2 o$ h8 ]7 W" ocancer —— good nuclear in bad cytoplasm!RNAs are cytoplasmic determinants determine  cytoplasm determine cell fate! division is differentiation is cancerous is life !& _0 A7 Z" s5 T  c0 X
2011-5-11 12:31
4 j8 y3 J( v5 q: Rcancer results from cell dedifferentiation...
; A1 z! O! p! C2 e5 P2011-4-28 18:07
: Z* ~, ~& p0 a% e- r4 ]8 {( jdifferentiation——asymmetric cell division !
# R6 `7 E4 j! ?1 R* r" U, S2011-4-28 18:04
) q; D5 e! V6 K2 t7 ecancer origins from the regenerative cells!
. w' F% a4 K2 L% e2011-4-28 17:527 W% G. G6 }& U* ]
Proliferation is differentiation potentiality!2 Y: L1 C6 ?# o
2011-4-28 17:49
2 n4 O5 h) j7 B4 p. W7 S8 iiPS——the key of Pandora box!
8 ^' z! I) W  M; J2011-4-27 22:36
& j4 h' B% S% x1 w: qAristotle— "The whole is greater than the sum of its parts."
0 S6 J) o/ @+ ~0 ~, B5 h2011-4-27 00:201 e  w, b) r' d; `) U7 M# b
cancer——atavistic cells
) L4 Q3 d9 k3 b, }2011-4-20 00:20" E$ M/ E$ A9 v6 }( ]0 k
cancer——cellular atavism!, L1 n5 J) M1 k8 N9 v
2011-4-20 00:18! a/ [$ T& T2 |% }  K
cancer——evolutionary ancestors of mammals.
7 v$ ~6 t& ]/ Y0 B6 q6 X4 R2011-4-20 00:09" E5 D" B  A, e) k  o% {4 Q& }% b
肿瘤是细胞自组织缺陷的产物 $ f2 E2 n- y" R/ R; x/ d5 X; ^3 Y% U
2011-4-17 01:41$ `5 y& _: v8 l5 Z7 l- u7 r
cancer——Metazoa 1.07 ]2 r+ Q* o) j( A6 W9 u" J
2011-4-17 01:00
/ f, [8 h3 n  d8 E, c. oUS——the Axis of Evil!
0 |8 o2 l+ O; |8 D$ b2011-4-4 01:19. n  G7 R+ c8 `) D& G
美国是世界的邪恶轴心!! B1 M6 O3 K# Z. B/ l/ Q- X
sunsong7: 沁园春.血               ---作者:萨达姆   日 本 风 光, 千 里 地 震, 万 里 海 啸。 望 仙 台 内 外, 废 墟 莽 莽; 东 京 上 下, 顿 时 逃 逃。 核 站 爆 炸, 世 界 惊 涛, 地 震 海 啸 试 比 高 ... (3-22 21:25)1 p: c7 L) U' m, S2 H% F: G
2011-3-22 19:06
$ E7 z0 a8 H( p6 rteratoma is derived from endogenous iPS!5 i8 g% f& e5 e& r" p% [+ Q' B
2011-3-15 21:44
( G9 b7 O1 I! Lips is a luxury gambol on  
/ F8 |: C0 \# C3 W2011-3-3 14:50
2 V0 D4 ~( I- ]& E- x- w; `cancer is intermediate of species evolution5 c9 n; F9 N; S. y4 C& u
2011-2-12 12:290 q9 q- w8 \' ]$ Q2 c
stem cell now is on the eve of coming medical revolution
9 O9 G: Y# b* g3 s% |$ S2011-2-12 11:20: m2 g6 Q: U; r& F
Inflamation is the reprogramming process of somatic cell in vivo!" ]2 O. |. o9 i3 X- b* N
2011-1-31 14:49
# P4 g2 v0 y; n( c2 }so-called medicine is niche regulator!; L* L4 G& B# i4 {' m/ i
2011-1-23 21:45
' s" ]+ l. g6 z3 N0 p- Fendogenous iPS is the cancer initiating cell!, `; J& L* }( i+ w
2011-1-17 16:474 a) `/ k$ J+ ~9 Y  o5 M
cancer is unicellular organisms!7 F9 |) \" ]/ C5 _8 `( ~( c
2011-1-9 22:04
1 M/ _! u) F2 ~Pandorabox Has Been Opened2 m7 ^! w, `" U5 C9 s
2011-1-7 23:24! X1 v4 m( g7 X7 Z% N4 J
iPS is the Emperor's New Suit ! 4 a) {  F8 Q& N2 F
2011-1-5 23:50
8 Z% A' x/ Z3 x' t& c; [, Ccell-free is the final solution of stem cell therapy
8 \) x+ u4 Z7 B0 k5 g; L1 L2011-1-5 21:46
  w' F! L' Q0 U; I- gniche is telling the story of stem cell...
' a& u3 J7 K8 ?" ]# \2010-12-29 17:321 J. `7 F, O2 y4 @+ u% @
cancer results from reprogramming of somatic cells
5 G  E& h2 |5 C5 v2010-12-25 18:56
3 Z9 ]& x7 S" H: c( N6 j- W, v$ }! icancer——good cells in bad niche!
- h% }- B1 _7 R  S2010-12-25 16:02
3 y7 K, Q, p9 Qcancer无罪——制造产生罪犯的土壤才是真正的犯罪!7 H3 A+ _) o2 _0 w9 O
deron: 灰常同意,有相关文献么? (12-19 09:41)
8 y' B( Q8 d$ }- s& q' P0 ~. gsunsong7: 呵呵,请来参加讨论——癌细胞的发生可能是一种“返祖”现象? http://www.stemcell8.cn/thread-32073-1-1.html (12-19 11:33)
4 X4 G& `4 B5 k6 L) [$ [sunsong7: 问题讨论 http://www.stemcell8.cn/forum-re ... 709-pid-246202.html (12-19 13:29)
% K, Y5 G* f$ B6 e2 f2010-12-18 15:54
2 {# x5 u# B5 K' Y4 j子曰:上善若水 大成若缺——干细胞治疗的终极解决方案将是不移植外源干细胞!' V3 ?$ g# h' D5 b
2010-12-15 15:077 S( t. G# F" e9 R* Z
老狼的记忆——大洪水
) {, W* X/ O$ L0 M2 ?' W# z# f7 i2010-12-13 23:25
* J1 H* u8 [7 Q$ v/ F( ~can cancer randomly differentiate into norml cell in vivo  
% q; G6 Q4 f/ F/ k) X4 U: I2 Q2010-12-13 22:33
- K' R7 g. C# E" N; vomnis cellula e cellula; w8 k8 S- J9 _3 z$ u
2010-12-12 09:281 r3 Y! A) `! o" Z( Z- a
Stem Cell ——The Origin of Disease
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