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本帖最后由 细胞海洋 于 2010-5-20 18:51 编辑 * n% L- D! C, E/ Q! g$ Y& C
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2 \: O9 n7 |* k' u" v$ s经典高引用次数专著,很多要用到microarray分析技术的朋友可以参看下。* A; {+ u, N! C
* e* X& a' L+ q, {+ G, w2 a在拿到你的microarray数据后,不知道分析的话面对上百的上调/下调基因、microRNAs表达谱变化或target genes会傻眼的 6 ~% h" a( i [+ m# D& ^& b
/ p) C3 y! U" S9 _. {2 uEditorial Reviews
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, } d3 t" C1 I+ s+ I1 E5 I: K W"This book should be required reading for any (future and present) post-genomic researcher..."0 C+ b$ d0 V5 f
— Sean D. Mooney, Briefings in Bioinformatics 3 E# R0 L# ^( {/ p8 [
Product Description
, t% O4 M1 b5 @Functional genomics--the deconstruction of the genome to determine the biological function of genes and gene interactions--is one of the most fruitful new areas of biology. The growing use of DNA microarrays allows researchers to assess the expression of tens of thousands of genes at a time. This quantitative change has led to qualitative progress in our ability to understand regulatory processes at the cellular level. This book provides a systematic introduction to the use of DNA microarrays as an investigative tool for functional genomics. The presentation is appropriate for readers from biology or bioinformatics. After presenting a framework for the design of microarray-driven functional genomics experiments, the book discusses the foundations for analyzing microarray data sets, genomic data-mining, the creation of standardized nomenclature and data models, clinical applications of functional genomics research, and the future of functional genomics.
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5 h' ]: G4 C" E9 S4 t8 t% \. Q, n" xProduct Details
. W; V3 K0 B) t& d4 UHardcover: 326 pages ( r7 R: F1 e8 G, `9 q
Publisher: The MIT Press; 1 edition (August 21, 2002)
/ h8 z! y/ _4 e1 g9 }* aLanguage: English
! X; X/ D$ X; KISBN-10: 026211271X
) l e9 E/ D2 V) B* dISBN-13: 978-0262112710
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Introduction
! ~& ]# |# O1 c7 {9 D0 r# L介绍请参见Amazon
; v! D! r( g* i+ mhttp://www.amazon.com/Microarray ... cular/dp/026211271X' W+ S. e) \7 t; i0 k, H m" n
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