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sunsong7

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发表于 2019-1-8 21:46 |只看该作者 |倒序浏览 |打印

"genetic mutation" should be exactly as "gene self-editing"
2017-12-1 13:17! k9 J9 x4 N1 h$ c
Bioreactor in vivo would be the terminator of illness.
2017-11-20 23:09% S) o7 O" z4 X5 [$ S
renew tech：剔除衰老（病变）细胞占位可以恢复青春。, F: |' F. H- h& z9 b3 @
2017-10-23 12:500 _1 H# d/ r5 R5 n. d' F$ u
魔不疯，鬼不魅；道非盗，仙非妖；神无形，兽无极。
2017-9-30 10:58( D# d& W  _; b9 O2 o
Life 3.0——from decoding and coding to reading and writing
2017-9-21 22:324 ?5 O2 f9 h! h4 x0 k- `
理论创新：亮明立场——先颠覆，再完善6 g7 @7 u. E$ M  `/ ^6 b
2017-2-7 00:07
干细胞第二定律：与细胞外基质共同构成多潜能；
2017-1-3 11:14; h8 {& }1 z/ q: ~4 U" s  H# b9 F
干细胞第一定律：全生命周期保持增殖分化能力；
2017-1-3 11:13/ u, F( s; c8 k7 }% t
NgAgo——Never give A guideline operated！
2016-12-1 10:09
表观遗传—— 一切皆可改变  一切皆有可能% G$ ^2 N; @/ T5 J1 B, t9 d
2016-8-17 23:378 Q, `% n7 T0 k
子曰：吸血鬼疗法——养儿防病养孙防老
2016-5-23 12:05
NgAgo——Debug tool kit for mammal cells7 K1 U- L: \6 ~8 [8 n4 r; l
2016-5-9 13:09& u  H9 g% h  w5 c; M
公理之外皆需证明；科学命题皆可证伪。
2016-1-2 00:206 K; i5 ?3 p! A- \# ^% ?
低氧——破坏线粒体功能、诱发炎症、导致基因突变
2015-12-16 20:19  [3 l, E9 N6 ^
癌症——炎症部位组织再生过程中细胞去分化失控形成的幼稚化新生物。; G( x' o' v2 X- c! s( i2 e+ T4 t
hcoohboy: 一个有趣的假设~但是没有炎症就一定没有癌症吗？ (12-18 16:16)
sunsong7: 炎症与癌症同在，Hanahan D, Weinberg R A. Hallmarks of cancer: the next generation[J]. cell, 2011, 144(5): 646-674. (12-19 19:45)9 \5 }8 G7 J9 u, Q- W
hcoohboy: 3ks~ (12-24 16:45)
2015-11-18 15:54, u# i3 M, C+ e* J. f
抽象世界与客观世界的真理判别标准是不同的：在虚拟数学世界里，逻辑是一切命题的唯一审判标准；在客观物质世界里，证伪是一切定律的最终审判依据。- A7 }2 X# L! O8 v$ G9 Z( k
2015-5-20 14:138 z9 z& m  I: g9 w3 A/ k
传统生物学将死：进化论=自然神论基因轮=宿命论细胞论=活力论翻版。现代生物学曙光乍现：系统生物学=数学结构生物学=物理学合成生物学=工程学: x: K! g  @! p2 W2 u" s
helong: 系统生物学是把细胞、基因、进化、物理学、信息学（数学）、工程学等都打包起来的所谓新学科，目前只做到了简单组合，还没有达到系统集成阶段。合成学更多偏向于化学。 (4-21 19:28)
sunsong7: 方向对头，努力总会有结果的 (4-21 20:05)- \3 s: J" O3 P7 r1 F' x
2015-4-21 16:46
search and research is just disassembling the creature.& |9 ]7 p  a6 J! c# l
2015-4-7 17:01. H( r* a  {; D, V
selection is  the act of intelligence
2015-4-7 13:49$ r3 X) b7 t0 b( q' ]0 g
Genome fusion create neoplasm
2015-1-20 13:105 Y5 K+ h; l. o, J/ t) w1 |& ?
STAP——Stupid Trick  Against Professional ) e' h( W0 ]$ U; L2 A% Z
2015-1-1 19:29/ u0 k6 C5 n# R; z
information=structure=negentropy$ _( ?0 E8 b9 z5 x7 _
2014-7-22 17:36* S3 ?: h5 \+ L; h
Natural mutation does not result in new functional genes
2014-7-3 14:06! v: x' b! f+ |
life is wisdom creation instead of natural evolution
2014-3-27 09:339 N$ p; }' s% x: b6 }4 N
let us explore the source code of life !" {  p: s# G) g2 R/ S
2014-3-11 13:11
bio-manufacturing——processing，machining，casting，printing，3D prototyping，duplicating，cloning，life replicating.
2013-10-7 23:067 J( |, e8 Y3 K- s" h; M
induced abortion would give the key for curing cancer
2013-10-2 23:33) G; l4 P6 F1 c6 l! t
“key breakthrough” in molecular biology are entertainments
2013-6-16 11:50; V  Z: b- ?4 v* g
Rules Of Living：trial-and-error exploring，survival takes the legitimacy& y# I  q7 f& i3 T% |% l" I5 T
2013-6-16 11:27
Life is a set of debuging programs0 r" Z$ V' T2 y( N
2013-6-15 18:407 F% l0 n& a  F* [& {
current biology is closed，destined and agnostic，it is  the only contribution is to kill cells
2013-5-2 08:54+ P6 z" N8 [# A% ]
information，energy and construction are the new base stone of biology，instead of evolution，gene and  cell  tales
2013-5-2 00:51$ |! [9 b. y5 W8 A. n
virus is the messager of  the universal life network
2013-4-18 14:33& A: j: v2 n6 `
Genetic information doesn't improve cancer risk prediction
2013-4-1 09:20
There is no early diagnosis of cancer，but early prevention of it- Y  c! w  m  x/ g/ [+ s
2013-3-27 09:17
hypoxia maintains stemness or carcinogenicity) N' k, I0 U. D/ I+ c* b
2013-1-2 05:21
cancer is the living fossil records on origin and evolution of human being
2012-12-9 23:31  Q/ P! L/ y, ?: P( T
information island results cancer; R# Y3 K1 g& E2 _+ r" ^/ d% T/ S
2012-12-9 05:23
life is digital game5 D! G1 A/ W- W+ I6 k
2012-11-10 00:175 v6 d6 d9 T4 M9 M( b# `
cancer ——severe abstinence reaction of cells to niche addiction
2012-9-28 12:116 m( ?* m  b' |5 X7 w4 B% m
未来生物学终将回归物理(熵)及数学(分形)的美感9 a6 e, {6 E3 a$ p  E  p* `$ U
biomater: 熵理论适用于任务物质。。。。也适合于生命 (9-26 09:28)
2012-9-25 21:22
membrane holds the key to life( }( e5 }/ X& G, p
2012-8-19 20:24
Cancer is the default state of cells
2012-6-26 22:17; W: @$ f1 S  H# z6 c
mainstream cancer theories could be overthrown！
2012-6-25 15:43
carcinogenesis has nothing to do with the gene mutations but is  the result of niche reprogramming...
2012-6-7 09:36( h0 [8 `' N4 D/ f
every living organism connected with the water， one cell one world5 t5 s! L0 s: z3 M
2012-4-19 22:06
chemical structure of cancer cell determines it's biological function.... w+ @/ W! L+ }
2012-4-7 17:56
Mann tracht und Gott lacht! E/ T( g0 X" j4 F' a) n
2012-3-24 21:34* R: R: b( g+ I$ `  h6 s4 J
Darwinism or genetic determinism is a fairy tale！
2012-3-13 15:18
niche isolation is essential for cancer speciation
2012-3-12 12:07- g2 V* y& l3 y) H
Hybridization Creates New Species，Mutation results species extinction
2012-3-11 18:21* w3 M- |5 o/ D2 Q
ROCK may join the niche reprogramming.../ z7 v9 n) _. P( D3 p4 `/ }
yuhaoze: 这是篇文献吗？ (3-9 10:41)+ p, Y) ]. X) V: ~0 s
sunsong7: http://www.stemcell8.cn/home-space-uid-6268-do-blog-id-1211.html 突破：病人体细胞及肿瘤细胞长期体外培养（附原文） http://www.stemcell8.cn/thread-51419-1-1.html (3-9 10:46)" @( c% s/ |! p0 q+ w: K
yuhaoze: 啊，我看过这篇，还顶了呢，谢谢哈 (3-9 14:37)# q8 X- a+ b/ m
2012-1-19 10:521 F7 C$ M6 F7 R, v# u3 N( M# m$ x# L3 D
oncogenes are pseudoscience; e8 w0 f% a! _# M6 N% m
2011-12-29 13:55
gene mutation leads to variation or extinction, not new species
2011-12-29 13:28" l( M, O- T/ g9 e! S" A
oncogenesis is non-Darwinian event
2011-12-28 22:563 b& }6 o7 G9 Z' n0 c
disorganization activate neurogenesis activate oncogenesis 8 ^/ s" l" F& D! b3 \
2011-12-22 23:384 @7 D6 D8 E) P8 w. d+ B
MSC is cell feeder，tissue scaffold，immune firewall and biological glue0 j: X, B. v$ H
2011-12-19 19:461 |  f3 e5 }) U) v
cancer is Noah's Ark（species carrier and life explorer）6 {$ F: y) |2 C8 P3 {
2011-12-10 09:46# O% W# D. q5 _9 Z6 H0 \5 o# ?
cell fusion create new species, gene mutation induce variation3 B1 _: _7 F+ z- D
2011-12-10 09:361 p9 E3 n, I3 e) z2 M& V1 Q
GVT will be cancer terminator， Cytokine storm will be cancer preventor
2011-12-8 12:56
cell fusion results regeneration，reprogramming，neogenesis，atavism； cell division results differentiation，apoptosis，senescense，development;
2011-11-27 14:54
Cancer is between protozoa and mesozoa， not metazoa...
2011-11-27 00:25
cancer is neurological disease！ haha，I got it！& i1 ]+ H  m9 e, |, F
2011-11-22 22:06
you are cancer，fetus is tumor. 佛曰：汝既是癌癌胚如来
2011-11-12 11:27
cancer is the ecological invasion of hacker...
2011-10-5 10:31
microRNA is  negentropy？
2011-9-24 00:48- }4 M1 K# V) I2 c9 G5 R% I* l
cancer is the social problem
2011-9-9 23:33- K" y. t; V9 y$ i. ?9 k6 l8 X
Science is the games of nobleman or madman
2011-9-2 15:03' S% `5 P: n" W% Y& r" I( s* o
cancer resulted from disturbance of biological liquid crystalline state of ECM. G# s; ^$ W' W3 v# M0 H
2011-9-1 20:13* Q+ S: a4 T/ `7 |8 e
niche n-dimensions——space, time, momentum and entropy; energy, material and information flows; physical, chemical and biological factors；topological, thermal, and fractal influences...
2011-8-13 00:37
Second recession is coming？
2011-8-9 23:58
cancer may be from sexual reproduction of somatic cells.
2011-8-7 00:16: A7 l! K! _  M  G. k2 {" e
who determine gene？ genetic determinism is fatalism！% \/ s2 v/ T4 S8 ]3 J
2011-7-30 11:26, \' E$ J7 f4 @5 }0 _3 h9 P; j
niche reprogrammabllity is the key of solving cancer problems...* q) s. x* ]  q9 ^
songtianlong: i can't agree more!!!O(∩_∩)O~ (8-14 20:42)
sunsong7: hehe. thanks for interested in this topic, welcome future discussing (8-14 20:54)
2011-7-24 01:24
cancer results from acquired genetics alterations.9 x+ s- G- X; I1 f3 j
2011-7-20 21:37
CSCs are the low differentiated cancer cells in G0
2011-6-29 16:30
iPS future——in vivo direct reprogramming ...
2011-5-31 15:20
niche reprogramming——cell fate will be manipulated by cytoplasm - microenvironment interaction http://www.stemcell8.cn/thread-40755-1-1.html3 N! \) _& G' M( H, ]" l
2011-5-31 01:28
all the somatic cells of Mammals are totipotent ！& k" o1 G& k/ ?1 b9 N% ?
2011-5-22 22:22
miRNA——The manipulator of  cell fate！
2011-5-20 20:21/ ~, e- m+ N( z) M/ s
《Cell Stem Cell》means “cell is stem cell” 活细胞就是干细胞？
2011-5-17 12:38% D2 J7 A  J+ t# K. O7 N% X
cancer —— good nuclear in bad cytoplasm！RNAs are cytoplasmic determinants determine  cytoplasm determine cell fate！ division is differentiation is cancerous is life ！
2011-5-11 12:31
cancer results from cell dedifferentiation...& j- N5 Z# J- U$ L; X$ O
2011-4-28 18:07
differentiation——asymmetric cell division ！: ^" h% ^  K/ _- i  j
2011-4-28 18:04
cancer origins from the regenerative cells！5 h& B0 e: U' g. X$ g% ]5 C' t# G
2011-4-28 17:52
Proliferation is differentiation potentiality！
2011-4-28 17:49* N' [5 ~: _2 o* q
iPS——the key of Pandora box！* t; d% j" D5 [$ H2 U
2011-4-27 22:36( v$ j* F. }: |! g, \
Aristotle— "The whole is greater than the sum of its parts."* N4 q1 I% ~1 e% y) @4 F
2011-4-27 00:20% r. `0 I# a3 ?9 d7 L
cancer——atavistic cells
2011-4-20 00:20
cancer——cellular atavism！
2011-4-20 00:183 q, Z. |+ K; c* f7 H) m
cancer——evolutionary ancestors of mammals.- Y5 h  n6 }; ]' D! f3 x$ f
2011-4-20 00:096 |5 `4 ]) v$ w
肿瘤是细胞自组织缺陷的产物 ' m: }0 p, r' F: }  I
2011-4-17 01:41
cancer——Metazoa 1.0
2011-4-17 01:003 E' n* \- M) A! ]7 c8 m- r
US——the Axis of Evil！
2011-4-4 01:19
美国是世界的邪恶轴心！
sunsong7: 沁园春.血            ---作者：萨达姆   日本风光, 千里地震, 万里海啸。望仙台内外, 废墟莽莽；东京上下，顿时逃逃。核站爆炸，世界惊涛，地震海啸试比高 ... (3-22 21:25)
2011-3-22 19:06  U( L' _7 C- c
teratoma is derived from endogenous iPS！% j/ N; ~" C$ c+ R
2011-3-15 21:44  e8 Z3 s2 b+ l/ N
ips is a luxury gambol on  . h8 C5 G7 t& M9 _' U* T
2011-3-3 14:50
cancer is intermediate of species evolution
2011-2-12 12:29
stem cell now is on the eve of coming medical revolution" t/ Q" ^8 K( W% u
2011-2-12 11:20
Inflamation is the reprogramming process of somatic cell in vivo！
2011-1-31 14:49/ N$ S( W# [5 g
so-called medicine is niche regulator！" P: ?' K5 O! w9 z) ?0 I
2011-1-23 21:45
endogenous iPS is the cancer initiating cell！1 w" `7 G. Q  F% L, d4 Z5 d
2011-1-17 16:47- a3 ?7 V, u7 I: z0 E9 b- r0 M
cancer is unicellular organisms！* w9 [% A2 [6 O- E
2011-1-9 22:04: S2 k5 u' ~( D
Pandorabox Has Been Opened
2011-1-7 23:24
iPS is the Emperor's New Suit !
2011-1-5 23:504 P" b. Y3 {  s6 d* i
cell-free is the final solution of stem cell therapy# C9 J+ q. P  y" R( c4 }' n
2011-1-5 21:46
niche is telling the story of stem cell...
2010-12-29 17:32& ~# y  g% [+ A& O) f
cancer results from reprogramming of somatic cells8 l, R: `2 O; i6 {: G' D8 k
2010-12-25 18:56  E; \; w$ D0 J: k! G& e4 Z
cancer——good cells in bad niche！- B* r1 ]$ x. r# ^# k% @% g
2010-12-25 16:025 W3 b* I6 W$ ^' U
cancer无罪——制造产生罪犯的土壤才是真正的犯罪！
deron: 灰常同意，有相关文献么？ (12-19 09:41)8 v# R) [6 i/ l# u
sunsong7: 呵呵，请来参加讨论——癌细胞的发生可能是一种“返祖”现象？ http://www.stemcell8.cn/thread-32073-1-1.html (12-19 11:33)
sunsong7: 问题讨论 http://www.stemcell8.cn/forum-re ... 709-pid-246202.html (12-19 13:29)
2010-12-18 15:54
子曰：上善若水大成若缺——干细胞治疗的终极解决方案将是不移植外源干细胞！
2010-12-15 15:07; V3 e- W" g% L1 L3 {: a
老狼的记忆——大洪水& f( G' {, X! S$ w; M6 F/ C# W
2010-12-13 23:259 g6 G0 g1 ], B9 W* ~
can cancer randomly differentiate into norml cell in vivo  1 a5 M1 h- |: O: I7 F' g7 Q
2010-12-13 22:33
omnis cellula e cellula
2010-12-12 09:281 d: T. q2 J6 Y; t, U' r
Stem Cell ——The Origin of Disease; E0 |6 {! _5 P, `: ]
2010-12-12 09:27

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