|
- 积分
- 4
- 威望
- 4
- 包包
- 16
|
本帖最后由 细胞海洋 于 2010-5-21 06:54 编辑
2 T5 F' R* M- k6 G/ e
; p3 r/ e* a8 \. r; u% l b李凌松*，王 莉
5 S/ z. ?2 G( K( Q! Y' N, m（北京大学干细胞研究中心细胞生物学系，北京 100871）: I3 X5 r& R% S3 z. }5 i* t
摘 要：胚胎干细胞具有自我复制并分化为人体各种功能细胞的潜能。胚胎干细胞具有的独特生物学5 g4 E7 @# p& q8 l1 S" m8 \% \! F, D
特性使其被广泛应用于生物学研究的各个领域，特别是发育学。同时，它潜在的医学应用也成为世界# f9 v$ |) N7 x/ n. F" N
范围内的研究热点。但是，由于人胚胎干细胞的来源为植入前的早期胚胎，人胚胎干细胞自诞生之日6 n* {4 |3 X/ P7 x1 c+ \
起便倍受争议。本文将从胚胎干细胞的来源、特性、鉴定标准、增殖机理、应用前景以及研究本身1 Y( y1 d$ K% }$ ~) [
涉及的伦理学争论给予概述。# N; ~- G: V0 ^( j1 M, z
关键词：胚胎干细胞；自我更新；分化；鉴定；胚胎生殖细胞；应用
' e" R9 r/ r4 F" G) E" n( @# _& {4 P中图分类号：Q813 文献标识码：A: j& [' A4 I% V" T
Embryonic stem cells
; F5 }2 M4 u t- ]" JLI Ling-Song*, WANG Li( @: L0 q" _3 \) q$ @
(Department of Cell Biology, Stem Cell Research Center, Peking University, Beijing 100871)
, F6 A( k8 I, n% i$ C' @Abstract: Embryonic stem (ES) cells are able to self-renew and differentiate into all kinds of human cells. Due to! b8 s# d: R; I" e, ]! b8 k
their unique properties, ES cells are used in diverse fields of biological research，particular in developmental
: W$ j2 j$ s$ m1 lbiology. Meanwhile, their potential medical application become a research hot-spot worldwidly. Since preimplantation
( F7 c9 r: R4 G& e4 }: teggs are sources to generate ES cells, the use of embryonic stem cells is therefore controversial.
" K2 s) r; W4 K# A+ N4 Z) u BThis review will outline characterization of ES cells, regulation of self-renewal, and the applications of the cell4 [/ e& ?: @/ z3 g; N; Y
in treating diseases, as well as ethical issues related to human ES cells research.
: ]* I) K, p6 X7 }9 m6 A$ bKey words: embryonic stem cells; self-renewal; differentiation; characterization; embryonic germ cells;" E- q! M" ?: _0 M* U
- |8 q+ D4 m) \附件为全文，请大家支持一下 回复本贴就可以下载了7 y- f ?1 ?7 h* R
/ H7 \! b6 s0 q& U/ `( a* h |
附件: 你需要登录才可以下载或查看附件。没有帐号？注册
|
发表于 2009-2-27 10:29
发表于 2009-7-14 15:44
