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2014年3月20日 Nature1 @5 V* i% i ?
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The motion-detecting cells of the retina, called direction-selective ganglion cells (DSGCs), have been known about and studied for more than half a century but their precise role in visual processing has remained unclear. Using a combination of genetic, anatomical and imaging techniques, Andrew Huberman and colleagues investigate the connections made by DSGCs in the mouse brain and find that they link specifically to neurons in the superficial layers of primary visual cortex. Inputs from several different DSGC types are combined to convey both directional and orientation information to the cortex. In addition, non-direction-tuned information from the retina is sent to deeper layers of cortex. This reveals that the mouse visual system contains several functionally distinct parallel pathways and that directional and orientation selectivity in the cortex may arise from the earliest stages of visual processing involving motion-detecting cells in the retina. Cover: Kelly Krause/Nature — Santiago Cornejo/Shutterstock
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发表于 2014-3-23 17:24
