《细胞》[Cell]13年7月3日出版pdf全文

nero1981

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On the cover: Developmental mechanisms generate
0 C9 s( s4 r8 a! Vinterspecies hybrids that cannot propagate, as alluded to by the artist's
7 r# w. `6 V3 Y( n; Fdepiction of the mythical Minotaur's labyrinth on the cover. However, even * @' e7 M* a1 R; a  F
socially na?ve animals rarely mate with members of other species. The mechanisms 7 v/ B7 }! Y4 Z9 V' e% l* }
that control such behavioral reproductive isolation, an important tenet of ! ?0 V# ~- ?1 T
evolution, are not well understood. As depicted on the cover, male flies tap 5 H8 e% v$ ?& Q5 n
other flies with their foreleg prior to attempting to mate. Fan et al. (pp.
2 z; P1 O' _- r9 H; G89–102) show that foreleg removal permits males to mate with flies of other 9 Z& x9 ]% K" }  w0 a( C
species. Activation of foreleg neurons expressing the chemoreceptor Gr32a is ! a- h* ?. i# L- g7 f
necessary and sufficient to inhibit interspecies courtship by D. 5 _6 ?% O2 ?* a6 Q1 c  x
melanogastermales. Gr32a is required to detect aversive hydrocarbons found
) s- l1 V  {( M) _5 Hon the cuticle of other drosophilid species, and one such hydrocarbon,
, L- {3 X# e- H; e: ^# ^1 }z-11-pentacosene, is visible on the female fly on the cover. Strikingly, female / t( Y: c# k1 V* H" Q2 y0 \; R
flies utilize a Gr32a-independent mechanism to reject males of other species,
" ?+ T5 J% A$ ?8 e, \4 swith the cover depicting the female fly rejecting the male who is tapping her.
1 g2 {+ Y4 E$ @7 s/ fCover art by Julie Newdoll.
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yuheng

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tpwang

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cz200203

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exin11

懵懂干细胞

千呼万唤始出来 谢谢

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eley

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MZzhang

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