PDF电子书：PROTEIN ENGINEERING （2012）

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. Z! V1 @8 ~4 G% o$ ]PROTEIN ENGINEERING, w- f" w! W( C1 h& K2 H5 k9 r
Edited by Pravin Kaumaya3 t' n# w* O' t- k0 |& k6 a
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Copyright © 2012 InTech9 H& f3 E4 G1 h/ _# ~" {+ k) e
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Contents
3 V3 s+ _4 w' r2 K( @5 zPreface   IX
, F3 T  [8 C; i4 U+ B$ _" D7 K8 CChapter 1   Structure-Functional Insight Into Transmembrane Helix Dimerization   1
  L- p3 H( P8 i4 v% MEduard V. Bocharov, Konstantin V. Pavlov, Pavel E. Volynsky, Roman G. Efremov and Alexander S. % p2 S: p5 ^8 [' d
Arseniev
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4 ]4 L( r& w- k0 EChapter 2    Protein Engineering Methods and Applications   33
* N, o2 k: N3 J. {6 [/ n6 bBurcu Turanli-Yildiz, Ceren Alkim and Z. Petek Cakar
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. R& y9 w1 ]$ vChapter 3   Evolutionary Engineering of Artificial Proteins with Limited Sets of Primitive Amino 3 d; W" h/ Q. r8 O* n
Acids   59 Junko Tanaka, Hiroshi Yanagawa and Nobuhide Doi. i6 U, ^; b+ U9 O) a; E7 b

0 J& l4 W' f, ]: i- S# ]Chapter 4   Protein Engineering Applications on Industrially Important Enzymes:
. D" S( B$ u! z  b  x0 v# k! ACandida methylica FDH as a Case Study    758 }5 C0 n, N6 o* j1 k
Emel Ordu and Nevin Gül Karagüler1 R7 Q# q2 O  C. j5 `6 M& E* ]5 E

. w5 L& ~# y8 u% ~0 Z3 }  K& g2 dChapter 5      Engineering High-Affinity T Cell Receptor/ Cytokine Fusions for Therapeutic
/ h' J- u0 Z4 |6 x! G0 G% QTargeting    99 Jennifer D. Stone, Yiyuan Yin, Min Mo,( o8 d6 _* O. P: K" k
K. Scott Weber, David L. Donermeyer,
9 b" W- L  @& R8 \Paul M. Allen, Roy A. Mariuzza and David M. Kranz: Q6 u" g# x3 ^0 j  x& O: L! T

4 i0 ]1 T; \7 o9 |- G! @Chapter 6    Molecular Evolution Within
/ B9 N; Y6 F( o9 v. @  hProtease Family C2, or Calpains    119
( q+ N6 U/ e% W7 Y$ s7 cLiudmila Lysenko and Nina Nemova+ z1 w3 D: q5 d4 J: P; j6 M
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Chapter 7    FN3 Domain Engineering   1458 q$ G" M1 E2 Y1 {
Steven Jacobs and Karyn O’Neil
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% r  Q& R# G* p1 W; W1 ~) j; DChapter 8    Engineered Derivatives of
$ L2 p% L# f1 \. uMaltose-Binding Protein   1637 ?% y7 M3 b1 k2 I) F
Paul D. Riggs
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. m" g  k$ S# Q7 JVI     Contents% `* X% t0 p5 t$ {
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# S$ ?) V9 p# O+ d3 _( }2 @Chapter 9      Applications of Bioinformatics and Experimental Methods  to Intrinsic Disorder-Based
3 ^! t1 ~# P) U, H4 X& ?Protein-Protein Interactions    181 Xiaolin Sun, William T. Jones and Vladimir N. Uversky
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* i- Z7 m8 A6 u8 `* b2 pChapter 10     Protein Folding, Binding and Energy Landscape: A Synthesis   207
  i0 k' C2 J( R# EShu-Qun Liu, Yue-Hui Xie, Xing-Lai Ji, Yan Tao, De-Yong Tan, Ke-Qin Zhang and Yun-Xin Fu
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Chapter 11    Protein Engineering with Non-Natural Amino Acids   253
* \2 G) Q8 C5 L( t  Q: j' AAijun Wang, Natalie Winblade Nairn, Marcello Marelli and Kenneth Grabstein
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Chapter 12    Generation of Xylose-Fermenting
" @/ h+ z4 ]% Y, e6 DSaccharomyces Cerevisiae by Protein-Engineering    291
) j( v: U) `2 X  xSeiya Watanabe and Keisuke Makino5 O. H4 {) C5 M$ m: f  }

3 o& B" x8 [4 l% K! }" jChapter 13   In Silico Engineering of Proteins' X4 `( q' z$ H' n5 [) m5 }
That Recognize Small Molecules    307 Sushil Kumar Mishra, Gabriel Demo, Jaroslav Koča and Michaela 7 N) N0 V; n- ~) B' v
Wimmerová& e: E! S1 g7 Y# n1 U4 J. w& {* U

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