哪些MicroRNA调控DNMT？

hughliang

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还有MicroRNA-29b
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# {6 A7 U- C' D* U5 U$ LMicroRNA-29b与DNMT3A和DNMT3B的3’非翻译区完全互补，能在转录后水平靶向抑制DNMT3A/DNMT3B的翻译，降低基因组甲基化水平，使被甲基化异常沉默的抑癌基因ESR1和p15INK4b恢复表达，诱导携带AML1/ETO的Kasumi细胞部分分化0 u" T) J( ]2 M9 y; p2 d4 T4 \
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MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1. Blood. 2009;113:6411-6418.