1998-nature-Dendritic cells and the control of immunity

andylee824

   B and T lymphocytes are the mediators of immunity, but their function is under the control of dendritic cells. Dendritic
" a3 r% m: C% n1 }6 m* Z6 E5 F0 Kcells in the periphery capture and process antigens, express lymphocyte co-stimulatory molecules, migrate to9 ]' o' M+ g  [$ W! K
lymphoid organs and secrete cytokines to initiate immune responses. They not only activate lymphocytes, they also) n: X9 [. Z+ n6 \; q: p
tolerize Tcells to antigens that are innate to the body (self-antigens), thereby minimizing autoimmune reactions. Once
' B% l  `( a' i4 c& R4 ]0 J- g5 x  z2 Ga neglected cell type, dendritic cells can now be readily obtained in sufficient quantities to allow molecular and cell
( m# s* O8 {; n: Obiological analysis. With knowledge comes the realization that these cells are a powerful tool for manipulating the
  x' G2 N" A# k" Pimmune system.

andylee824

自己顶一下！

andylee824

自己顶一下！