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回复 mecol 的帖子/ X- j& x* g8 _0 {" I4 e
- {9 f9 F* J7 X0 J$ Q( ?" k. v# t" nI would say the clone you got is not a fully reprogrammed iPSC. When somatic cells received reprogramming factors, cells were going to be different stages. They might die, apoptosis, transform, senescence et al. It is a very heterogeneous population. Some cells started to reprogram, but they stopped at different stages. Some cells go to a stage to iPSC, then go back to somatic status. Only a very small percentage of cells ultimately become fully iPSC. |
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