Mechanisms of Disease Cancer Stem Cells

richy

Craig T. Jordan, Ph.D., Monica L. Guzman, Ph.D., and Mark Noble, Ph.D.
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) A$ @+ l; y  r7 a  @The deepening of our understanding of normal biology has made
/ D: v+ |- _* c9 l1 Nit clear that stem cells have a critical role not only in the generation of complex
8 h6 f) b! }8 ^8 ?3 v* E8 k. Rmulticellular organisms, but also in the development of tumors. Recent* U6 L. N. d& V; ~: a( f* h) O
findings support the concept that cells with the properties of stem cells are integral
  t) \/ J2 J6 ^! d' Nto the development and perpetuation of several forms of human cancer.1-3 Eradication
! a0 v$ |9 w( }2 [( G* n" Eof the stem-cell compartment of a tumor also may be essential to achieve stable,3 J9 w# j/ ?  M/ u' V0 @
long-lasting remission, and even a cure, of cancer.4,5 Advances in our knowledge of
1 a# v/ k9 |3 Lthe properties of stem cells have made specific targeting and eradication of cancer. L% Y% s' m: R0 t( n* n
stem cells a topic of considerable interest. In this article, we discuss the properties, z# A" Y7 q; N1 P1 H/ ]8 C
of cancer stem cells, outline initial therapeutic strategies against them, and present
  U7 b. @  ?6 L( cchallenges for the future.# `  O7 R$ A* N& U/ x+ v
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efool

不错，很有价值

Fischer3

好东西，要顶！

ahmusht

have a look

Chris

like it 7 c8 Q' d* O9 s/ Q+ J
thanks

barton_nyd

好东西，看看啊

yolanda_sea

谢了

hualin840518

很好！

hualin840518

很好！谢谢诶！

15816126

good