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本帖最后由 telomerase 于 2012-4-23 12:23 编辑
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# h9 P+ |3 p; V% L, }9 j现在已有1-6,6个分册，7还没找到
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Stem Cells and Cancer Stem Cells, Volume 1: Stem Cells and Cancer Stem Cells, Therapeutic Applications in Disease and Injury: Volume 1 free ebook download
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Author(s):M.A. Hayat
/ k" s. H. D- SPublisher:Springer5 Z7 i- H' n+ G$ p0 t
Date:2011-10-284 ~8 Z$ J- H: y# m" F" i) I! G& t
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Language:English
U9 x+ H+ s( D3 n- E9 xISBN10:9400717083
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/ I- Y6 B4 u+ GOCR uality:ISBN13:9789400717084& H* u% U s; e0 Y( R$ ^0 C
Difference between tissue specific stem cells and embryonic stem cells is explained. The advantages of the latter are included. The application of human pluripotent stem cells, mesenchymal stem cells, and hematopoietic stem cells in cancer therapy and tissue/organ regeneration is detailed. Role of neural cancer stem cells in brain tumors, including their role in brain tumor therapy and the role of CD133 stem cell antigen in glioma patients, is emphasized. Therapeutic role of bone marrow-derived stem cells in myocardial infarction and the role of mesenchymal stem cells in orthopedics are explained. Transplantation of umbilical cord hematopoietic stem cells and allogeneic hematopoietic stem cell transplantation followed by graft-versus-host disease are presented. Role of cancer stem cells specifically in glioblastoma and medulloblastoma is included. It is also emphasized that CD133 is an appropriate stem cell marker for gliomas. Targeting of cancer cells is also explained.
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Stem Cells and Cancer Stem Cells, Volume 2: Stem Cells and Cancer Stem Cells, Therapeutic Applications in Disease and Injury: Volume 2 free ebook download
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Author(s):, Z' n4 N! X# B7 {- g3 L: K+ d
* q4 s2 N- j( y$ z5 O, y8 YM.A. Hayat# h2 ~" w4 D. w, r4 Z7 S
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Publisher:Springer Y3 X* K( K; \9 v3 |6 ^0 E
Date:2011-10-15
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ISBN10:9400720157- X- R i' S" q$ |: D
Pages:408
% u. ^5 r* F/ P" ?; bOCRuality:ISBN13:9789400720152
' Q- i/ }6 _$ _As in volume 1 of this series, this volume presents information on stem cells and cancer stem cells Therapeutic Applications in disease and tissue/organ injury. Methodologies of regenerative medicine and tissue engineering are major components of this volume. Specific stem cells discussed are: human embryonic stem cells, hematopoietic stem cells, cord blood stem cells, human pluripotent stem cells, gliosarcoma stem cells, induced pluripotent stem cells, intestinal stem cells, human thyroid cancer stem cells, tumor stem cells, menstrual stem-like cells, neural stem cells, breast cancer stem cells, allogeneic mesenchymal stem cells, fetal membrane-derived mesemchynmal stem cells, and omental stem cells. The method for isolating bone marrow stromal cells is explained. Method for generating marmoset-induced pluripotent stem cells, using transcription factors, is also explained. Use of stem cell lines in therapeutic applications is discussed. Programming of stem cells is described. Methods for transplantation of stem cells are presented. Use of various types of stem cells for conditions such as stroke, ischemia, heart diseases, Alzhemier’s disease, and neurogenerative diseases in general, is explained. For example, generation of human cardiac muscle cells from adipose-derived stem cells is included. Another example is repairing bone defects using mesenchymal stem cells and mesenchymal-derived endothelial cells. Differentiation of new neurons from neural stem cells is described. Method for repairing retina condition using human embryonic stem cells is explained these cells can induce neural differentiation. Treatment of graft-versus-host disease resulting from hematopoietic stem cell transplantation is elaborated.6 g# b G! T) O! r( O+ x. y2 F+ k
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Volume 3
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# b; A+ r' {0 ]/ @, o" ]6 W, T( xSpr ger | 2012 | ISBN: 9400724144 | 425 pages | PDF | 10,9 MB* x7 ?" e1 A5 B, H* f
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It is pointed out that cancer stem cell is a cell type within a tumor that possesses the capacity of cell-renewal and can give rise to the heterogeneous lineages of cancer cells that comprise the tumor. It is emphasized that a cancer stem cell is a tumor initiating cell. That conventional chemotherapy kills most cells in a tumor, but cancer stem cells remain intact is discussed. Vast applications of stem cells, cancer stem cells, mesenchymal stem cells, and human pluripotent stem cells are discussed. Because human embryonic stem cells possess the potential of producing unlimited quantities of any human cell type, considerable focus is placed on their therapeutic potential in this volume. Because of the pluripotency of embryonic stem cells, this volume discusses various applications such as tissue engineering, regenerative medicine, pharmacological and toxicological uses. The role of these cells in cell differentiation is also included. The role of cancer stem cells of breast, colon, and melanoma tumors in response to antitumor therapy is detailed. The role of cancer stem cells, specifically in the deadliest brain cancer, glioblastoma multiforme, is explained. Transplantation of bone marrow-derived stem cells for myocardial infarcation and use of mesenchymal stem cells in orthopedics are described.
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N0 H9 ^& }% c- O; `$ v3 [' u, MVolume 4
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& P, [: v) N, }0 _5 [; S+ NSp nger | 2012 | ISBN: 9400728271 | 338 pages | PDF | 6,7 MB: W9 e: K" j9 y$ E* I7 ^0 N
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It is difficult to overstate the potential applications of stem-cell biology to our understanding of, and responses to, disease and injury. This volume aims to bring to its readers authoritative and responsive coverage of aspects of the field that will keep them up-to-date in a fast-moving scientific landscape. The fourth volume in the series on stem cells and their cancer-carrying counterparts, this book sets out the plethora of therapeutic applications offered by a group of specific stem cells in tackling disease and tissue injury. The list of subjects includes embryonic, induced pluripotent, human hair follicle, bone marrow-derived human mesenchymal, adipose-derived, cancer, and breast cancer stem cells, in addition to periodontal/progenitor cells. The adaptability of human embryonic stem cells, which have the potential to develop into any cell type, ensures them an especially detailed treatment. Contributions explore the causal influence of cancer stem cells in malignancies such as cancer and breast cancer, and delineate the way mesenchymal stem cells contribute to the growth and metastasis of colon cancer. Shifting from disease to treatment, the text explains the therapeutic value of transplanting mesenchymal stem cells to the injured brain as an aid to its recovery. It includes material, too, on the exciting prospect of valuable new targeted cancer drugs borne of our increasing understanding of the molecular pathways peculiar to tumor biology. Key topics, such as the benefit of stem cell transplantation to immune system recovery among severe combined immunodeficiency patients, and the treatment of malignant gliomas using genetically modified neural stem cells as markers, provide a window on cutting-edge work in these specialized subjects. The extensive scope and detailed analysis of this volume, and of the series to which it belongs, mean that whether readers want a breakdown of the impact being made by cancer stem cell research on the design of next-generation cancer therapies, or details of the way stem cells could transform regenerative medicine by repairing damage to vital organs and tissues, they will find these��and much more��here.
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5 |" n! d( G6 Z; |9 iVolume 5
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+ [7 w+ Y# R) @! J2 j' \: A; LEnglish | ISBN: 9400728999 | 2012 | 328 pages | PDF | 6,6 MB
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5 Z! `) C% @$ X5 }' yIt is pointed out that a cancer stem cell is a type within a tumor that possesses the capacity of self-renewal and can give rise to the heterogeneous lineages of cancer cells, which comprise the tumor. It is emphasized that a unique feature of cancer stem cells is that, although conventional chemotherapy kills most cells in a tumor, cancer stem cells remain intact. Vast applications of the following specific stem cells in disease and tissue injury are discussed: embryonic stem cells, human mesenchymal stem cells, cancer stem cells, arterial stem cells, neural stem cells, cardiac stem cells, dental stem cells limbal stem cells and hematopoietic stem cells. Because human embryonic stem cells possess the potential to produce unlimited quantities of any human cell type, considerable focus is placed on their therapeutic potential in this volume. These cells are used in tissue engineering, regenerative medicine, pharmacological and toxicological studies, and fundamental studies of cell differentiation. It is pointed out that the formation of embryoid bodies, which are three-dimensional aggregates of embryonic cells, is the initial step in the differentiation of these cells. Therapeutic implications of signalling pathways in cancer stem cells are pointed out. Targeting self-renewal pathways in cancer stem cells are also included. Application of mesenchymal stem cells for treating ischemic brain injury is explained. Neural stem cells proliferation into the surrounding area of the traumatic brain injury is explained. ( \: U* K1 l, O# l m3 A
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Volume 6
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1 I( M2 h" b s9 m% yEnglish | ISBN: 9400729928 | 2012 | 471 pages | PDF | 8 MB
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The difference among pluripotent stem cells, multipotent stem cells, and unipotent stem cells is pointed out. Vast therapeutic applications of the following specific stem cells in disease and tissue injury are discussed: human embryonic stem cells, human mesenchymal stem cells, germ cell-derived pluripotent stem cells, induced pluripotent stem cells, human umbilical cord blood-derived stem cells, breast tumor stem cells,and hematopoietic stem cells. Because of the potential of human embryonic stem cells to produce unlimited quantities of any human cell type, considerable focus is placed on their therapeutic potential. Because of their pluripotency, these cells have been used in various applications such as tissue engineering, regenerative medicine, pharmacological and toxicological studies, and fundamental studies of cell differentiation. The formation of embryoid bodies, which are three-dimensional aggregates of embryonic stem cells, is explained as this is the first step in cell differentiation. Such embryoid body culture has been widely used as a trigger for the in vitro differentiation of embryonic stem cells. The basic capacity of self-renewal of human embryogenic stem cells is explained. The role of TGF-beta in the propagation of human embryonic stem cells is discussed. The differentiation of human embryonic stem cells into neurons, hepatocytes, cardiomyocytes, and retinal cells is fully explained. Donor policies for hematopoietic stem cells are also explained.
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发表于 2012-4-22 10:13
发表于 2012-4-22 10:18
