Adult mouse bone marrow stem cells can become cells of the nervous system

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日期: 2003-08-19 今日/总浏览: 1/435, K' r2 K. i7 z: _

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UniversityofMinnesotaresearchersshowthatadultbonemarrowstemcellscanbeinducedtodifferentiateintocellsofthemidbrain.Thefindings,publishedintheonlineearlyeditionoftheProceedingsoftheNationalAcademyofSciences,suggestthatadultbone-marrow-derivedstemcellsmayonedaybeusefulfortreatingdiseasesofthecentralnervoussystem,includingParkinson'sdisease.
( T; H: W" N2 b  F; [2 yThepotentialoftheseadultstemcells,termedmultipotentadultprogenitorcells(MAPCs),werethesubjectofresearchreportedinNatureinJune2002.Today'spublishedresearchfindingsshowspecificcelldifferentiationforaspecificgoal.Whilethistypeofcelldifferentiationhasbeenshowntooccurfromembryonicandneuralstemcells,thisisthefirsttimeadultbone-marrow-derivedcellshavebeenshowntogeneratedopaminelikeneurons.  c5 T( E' }3 _5 B  {# \
We'reabletoshowinvitrogenerationoffunctionaldopamineproducingcellsfromadultbonemarrowstemcellsneededfortherapyofParkinson's,saidleadinvestigatorCatherineVerfaillie,M.D.,directoroftheuniversity'sStemCellInstitute.ThisfurtherprovessimilarityoftheMAPCswithembryonicstemcells.
5 z. Q& e% ?( d8 RAgain,whileadultstemcellsholdgreatpromise,sidebysidecomparisonofadultandembryonicstemcellsmustbedonetodeterminewhichstemcellsaremostusefulintreatingaparticulardisease,saidVerfaillie.
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来源: University of Minnesota0 j" k9 L0 k0 t
发布者: 亦云