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原文出处：http://www.abc.net.au/news/2013-06-04/stem-cell-research/4732158
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Australian scientists have created a test to work out whether certain types of stem cells are unsafe.
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The CSIRO has spent five years developing a safety test for induced pluripotent (iPS) stem cells.7 c* f3 { \% c0 {' E
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iPS stem cells do not require a human embryo and are considered an important research advance.
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Last month, scientists were able to use human skin cells to create early-stage embryos./ J" i) G: c2 T
# @+ ]1 F8 E' Z; [. n( [. XThere is much debate in the scientific community about the advantages of iPS stem cells over their embryonic counterparts.) O$ f6 l9 X& X6 a( t6 I
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The CSIRO's Andrew Laslett says there is still a number of question marks about the long term stability and safety of iPS cells.* I) d' U( i% p% r, t
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"At this stage it appears that human embryonic stem cells may be slightly safer, but it's early days," he said.+ Y7 E, w+ f$ J$ ~/ k- Z2 P8 ~6 H
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Dr Laslett says the new test will provide more information about the quality of iPS and help identify unwanted cells that can mutate.
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"Sometimes the cells that are made from the iPS cells change back into stem cells which are unwanted because these cells can form tumours called teratomas," he said.
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, b" [% F$ O2 o6 A) SDr Laslett is hoping the research will be used to ensure stem cell therapies are safe for humans.
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2 a/ {, T; i5 T) @! H, i' B0 _"Any cell line that's going to be used for cell therapy has to go through a whole barrage of different tests to see whether they're safe," he said.. n! b' o9 L1 K3 O' h( H" x5 R
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"We hope that this one will be added to that number of tests... and it's really the first one that's entirely specific for human induced pluripotent stem cells.", c( T/ _% C) _% n4 J* o2 l
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发表于 2013-6-5 11:23
发表于 2013-6-6 11:45
