Hierarchical Maintenance of MLL Myeloid Leukemia Stem Cells Employs a

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Hierarchical Maintenance of MLL Myeloid Leukemia
& {; \* D: D: v! `Stem Cells Employs a Transcriptional Program5 h' R, Q2 Z% M; D* @2 q" i
Shared with Embryonic Rather Than Adult Stem Cells
- {& ]2 h/ G5 ^: K! R% c, ITim C.P. Somervaille,1,4 Christina J. Matheny,1 Gary J. Spencer,4 Masayuki Iwasaki,1 John L. Rinn,2 Daniela M. Witten,3
4 u' U" X. @9 W# d+ H( [1 BHoward Y. Chang,2 Sheila A. Shurtleff,5 James R. Downing,5 and Michael L. Cleary1,*
3 N" ?: b! _8 D- V, k7 C1Department of Pathology
' L8 a) ?- u' {' M2Program in Epithelial Biology/ J* |' K: H0 R5 d( ]2 p: p# \& u6 V- q
3Department of Statistics/ x+ u3 Q% ?  o& l) R* Z4 i% T" [
Stanford University, Stanford, CA 94305, USA; z2 T! c" g6 z) C1 G( I
4Cancer Research UK Leukaemia Biology Group, Paterson Institute for Cancer Research, University of Manchester,5 a. d8 ]! z& s" |
Manchester M20 4BX, UK
! P! M$ L- m* s" Q! b2 c5Department of Pathology, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA# l1 ~8 ^$ A9 [  f: v5 c2 u% `
*Correspondence: mcleary@stanford.edu
4 e# n8 `% r7 s  uDOI 10.1016/j.stem.2008.11.0158 n* B7 Z. t5 ^) h4 i
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guoguijie

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tspaulzhao

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pau10

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may21thwlp

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金鹤

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