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本帖最后由 细胞海洋 于 2010-1-19 08:22 编辑 % d5 x$ G" K, b* R$ y$ E% ^; o) s
4 I7 q$ f; a4 |. @0 TGenes and common diseases presents an up-to-date
' S5 u6 e6 d! y8 K8 s5 fview of the role of genetics in modern medicine,# y% Y: u5 C( z% K7 b; \
reflecting the strengths and limitations of a genetic' M5 F: t$ h# s5 o
perspective.
$ u# b/ l3 Y: T9 f2 X% R: n0 l; T" nThe current shift in emphasis from the study of; l; [+ L3 {- u4 w+ s4 J5 k
rare single gene disorders to common diseases
0 D l8 c6 C8 jbrings genetics into every aspect of modern! F8 K9 Z# J2 ?7 T
medicine, from infectious diseases to therapeutics.
& `5 I8 G* L! P1 C2 xHowever, it is unclear whether this increasingly' a% R. r b; l% z5 b8 Z, y/ \
genetic focus will prove useful in the face of major& F) M; W7 ?8 B4 b/ t& q& F
environmental influences in many common
) S' P7 a: Z, Q3 t$ A! {diseases.
) T2 N* @8 i9 W5 A6 w& o! u( hThe book takes a hard and self-critical look at
# T/ I! t! R& o6 A8 ?what can and cannot be achieved using a genetic
5 H2 Q3 C8 b3 P1 R B; g: F: Tapproach and what is known about genetic and4 u- i9 G. r1 h9 A ]" z* y2 n+ Q
environmental mechanisms in a variety of) T& T' @4 i% n5 {8 O5 ^2 n
common diseases. It seeks to clarify the goals of
5 V9 b% e; w( b% x' jhuman genetic research by providing state-of-the
' E5 i1 I! D, v+ b- w2 e5 Cart insights into known molecular mechanisms
. B1 n8 J/ M, f6 j Yunderlying common disease processes while at the
8 H7 W; R) _9 ~! v& x* ]/ p# qsame time providing a realistic overview of the
! {; H4 |9 e" M E% H! jexpected genetic and psychological complexity.
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+ a0 K3 u- r1 o; s( G- j$ A+ `! _8 ?* h+ p2 K' f
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