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- 积分
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可是这个版本（如果是，我就给你下）：) `/ j7 l4 d% ^# t
Table of Contents
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$ |/ v) ]3 `+ k! o/ |I. Principles of Developmental Biology
z- k# V2 [ U' b
' r" a% }+ G) D: R1. Developmental biology: The anatomical tradition
' X; o& H; l. r. W5 [# J0 JNew techniques of mathematical modeling of development( V; z. n9 ?: {- [ V" {
2. Life cycles and the evolution of developmental patterns3 @ b8 n3 \- l0 ^1 k
Recent advances in planarian regeneration
; S5 P2 x4 Q# _$ ]3. Principles of experimental embryology+ [/ f8 x' e7 R) u0 a
4. The genetic core of development
8 M: I& ?! Z8 p+ Q% \5. The paradigm of differential gene expression
" S C9 a0 q9 E* e' G8 xHistone modifications* W* Q; e3 w2 `2 W4 J0 U! h
MicroRNAs
4 {; ]: c. W/ ?Pioneer transcription factors2 t9 r6 P# i% G
Mammalian cloning and methylation patterns
5 [8 X3 F& H' O. P6. Cell–cell communication in development
$ s) r6 |: S$ a! x3 m) T# x2 C5 X$ WStem cell specification and stem cell niches! \+ R; o; }! i$ D
Morphogenetic regulation by cadherins
8 L1 |# z; g* w5 Z! zNoncanonical Wnt pathways
, J9 g9 n0 ?6 xDependence receptors and apoptosis- b" @4 k: Q& w0 J l/ c* f' W
Community effect and autocrine factors
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II. Early Embryonic Development8 X0 @- {* ~- ]) D( y& j4 W" _
! b) e. g ?4 ?! y# w- i
7. Fertilization: Beginning a new organism' d2 _5 [: T6 v" o4 ]# t6 \3 | A
Cortical granule components
2 V9 l x7 @. f1 H- @New mammalian sperm–egg binding model
- F% B7 \8 c8 }7 x& U& X) OMammalian sperm chemotaxis and thermotaxis, _" i! |2 w) x* {; p
Mechanisms of sea urchin sperm chemotaxis
5 V. t. z7 Z9 @8 ^1 zSea urchin bindin receptor
J" p4 n6 K) z L& iOocyte translation inhibitors and their removal
2 E3 b2 \/ d/ G6 RNew hypotheses of sperm activation
: n1 H! r, T7 i$ o! e! `1 a8 pMammalian sperm–egg fusion
9 P; d% ?# g; |4 W7 I4 `8 l# x8. Early development in selected invertebrates
$ z; Q2 I( i+ f( M+ z9 f, FWnt and Nodal in sea urchin axis specification; h. H: f8 ~" l$ F) p' D/ |
Coiling genetics of snail embryos
: ?* f" V8 a8 P$ NFunctions of tunicate yellow crescent3 f2 r' U$ G2 [, H
Roles of FGFs in tunicate development5 V2 H/ K6 Q9 U. c! a
Tunicate heart development7 E5 q1 f. p' u# k
9. The genetics of axis specification in Drosophila
/ ~& j0 H9 G% p: H. RFGF signals and Drosophila mesoderm formation
& L9 {+ m' C4 w4 t+ e" QTransport of Nanos and Bicoid messages to opposite ends of the fly oocyte# v. b8 U4 h+ @) P* C7 y# P2 I% D. @1 I
New model for gap protein stabilization) |0 ]( H9 G' S! U* N& c$ c
10. Early development and axis formation in amphibians
k# S U8 M: m, I6 qNew models for organizer formation in Xenopus
: L: u, |& T6 s. QNew model for mesoderm specification in Xenopus/ h' Q' H% ]4 x& n8 n
11. The early development of vertebrates: Fish, birds, and mammals
0 r- M: a( N$ [Maternal effect mutations in zebrafish
) V ?1 c8 z7 F" ^" ^Neurulation in zebrafish" w- {4 o$ }' l( c7 Z
Retinoic acid in anterior–posterior axis specification in chordates% }# \/ y# T% g. j% y. M" ?
Ciliary movements and left–right axis specification in vertebrates
0 ~0 l( r/ S+ | p5 jRole of Cerberus in chick head formation, _" e8 d. t: s: }4 [& L
Mesoderm specification and migration in chick gastrulae
. }5 A4 {% z, E% @+ ?5 {FGF and cell fate in chick and mammalian epiblasts+ K" Z- A5 C" r9 M1 n; w
Induction of pluripotency in mammalian inner cell mass blastomeres
! F9 {& n( @& d' Q3 `Homeotic transformation in mammals due to total Hox paralog knockouts1 |! p9 V4 N1 q4 y! h6 I
Controversy over blastocyst polarity in mammals
8 h4 W- ?/ U$ S3 ^ KFolate receptors and teratogens affecting neurulation6 l1 h! c% }$ |( L& v! d) x
8 R" D+ s# F5 H ZIII. Later Embryonic Development" o1 q4 j# m) y9 L% O3 Q! w9 N
' g# B1 I7 ]3 ?- e+ [2 l12. The emergence of the ectoderm: Central nervous system and epidermis
' z+ X+ U! r _! h$ KGenes specifying neural fate
% k+ e' r# O2 k3 I& B2 SHuman-specific genes specifying brain growth( J e3 `6 D* u, P4 I
Progressive myelination of the human brain6 f1 C5 H2 x& |. ]' d% M' k
Neural stem cells# Z! {: y, B% v7 a* z/ x. F9 _
Eye development and blind cave salamanders8 a+ W; |- r( b m
Skin, hair, and pigment stem cells8 o' @. f! F! W: F( C+ i
13. Neural crest cells and axonal specificity
5 F" Z& J$ }6 |) I- lNeural crest cell specification and migrations
" q6 ^& d6 K0 ]' V& v9 aHead vs. trunk neural crest specification. r& b( p3 K' p! j. I+ l' r- M* p
Neural crest-endoderm interactions forming facial structures
( m8 M' g' `: G3 DPlacode specification and separation* l/ ?: k' T1 Y8 p4 o j
Tooth development and evolution& m7 T0 J) h2 J0 Q" u/ D ^
Semaphorins, Robo, and ephrins in neural patterning( T' Y9 u$ I0 t& S" q1 D
14. Paraxial and intermediate mesoderm
. x2 x+ K) d; c3 E& E' hSpecification of paraxial and intermediate mesoderm
8 p. l# X2 z( n; `Epithelialization of somites
1 e$ h. N* @. ~& t( tThe syndetome—where tendons arise+ R' E W) h( D* x& n# o
FGFs, Notch, and Wnt in somite specification and separation) i0 q. u0 F+ [; I
The primaxial and abaxial musculature
2 K, Q/ N# N! G+ H8 ^* W% |New sources of muscle precursor cells
' K, w8 B3 `* m5 aPathways of skeleton formation
) g! i$ K7 C$ E2 Z" x% v' k/ aRegulating ureteric bud branching
8 g/ _' n# J( E1 v4 [( t! }/ A6 h. lWnt and FGF proteins regulating nephron formation2 ?" v N4 U* X9 l
15. Lateral plate mesoderm and endoderm7 b9 P, W- s1 H! S- B- |
Cloaca formation
0 S! [+ K' l- R# h6 E% w; yHeart cell specification1 Z/ I. o7 t3 j
Tbx genes, retinoic acid and heart chamber formation
- S0 d0 Q u; U: FHeart valve development
3 z* s# ?$ r8 W" E. JHematopoietic stem cells and their derivatives
6 q- s9 ]4 v7 d% `/ eLymphatic development" ?9 E u% _- L! S+ m/ t
Induction of arteries by neurons" B* b/ c/ Q- J: Q
Placenta as source of blood stem cells
8 B6 }' ]' Q) }7 y3 CAdult blood stem cell niches$ R+ d* I2 F( O
Endoderm specificity8 `- x5 s& y& w
Pancreas vs. liver development
3 z0 I) H" g/ n# j; H ]' a( d) E% gFate mapping pancreatic cells- Q5 d! B, ~# Q" Z- B3 m, O. G
16. Development of the tetrapod limb2 V2 ]1 g% {) {! `' g/ k# L1 T
Hox code of limb development
) H7 }4 d) R7 v& ?: \: hSpecification of the digits by hedgehog proteins and HoxD genes6 b( k/ [3 f1 F' b# k. q
Controversy over digit identities in dinosaurs and birds7 F/ B0 l+ T% w2 X( V
Getting limbs from fins
; ]9 ]3 X5 Q& V2 L" k m5 v2 m8 Z17. Sex determination+ ]; D4 [& }- k: k+ J& e8 G
Timing and gene expression in mammalian sex determination
- a" R1 `5 Z: p; |$ Y% dBrain sex determination pathways in vertebrates and flies: y- m* W: K: X
Hormone disruptors and sex determination problems
# j! @0 u6 F- F# j9 lDosage compensation and sex determination
. {! c- X) W. [2 k* ^# `Temperature-dependent sex determination in turtles
! D7 R' m V! L. S6 {$ b$ l18. Metamorphosis, regeneration, and aging
$ n7 g: {4 F( l& L( A# wMolecular mechanisms of amphibian metamorphosis
+ y4 E1 X) I3 R) P: B2 ZEcdysone receptors and the response to molting hormone: O1 k8 Y; [3 \: ~/ S
Compartment formation in the wing imaginal disc$ Z3 ?' q) |) W% W/ j! y
Why can’t we regenerate our limbs?$ M% A9 s5 D1 m+ A0 p4 `% f
Neuron- and mesenchyme-dependent stages of limb regeneration
" F0 l& g0 R/ l/ [: R% k4 d' }2 zSpecification of limb regions by transcription factors during regeneration
' W+ p7 }4 H- fMitochondrial control of aging9 L6 G/ q0 x* V" l# R
Insulin pathway control of aging and possible relation to oxygen radicals: f5 j8 n5 C$ P: m5 M) x. }
“Ageless” animals and environmental control of aging
$ D1 _8 k) c, @) r* g19. The saga of the germ line
) u. m% v5 s1 J3 XGenetic specification of germ-line cells in Drosophila and vertebrates
# {2 c3 O' y4 iComponents of the Drosophila germ plasm. M, L: L+ {# M) G( F, P" [* V
Egg and sperm stem cell niches in Drosophila
( `8 ]' v) r( nMigration of primordial germ cells in mammals, chicks, and flies
$ W- [2 J' o" Z0 iDetermination of meiosis and mitosis in C. elegans& b, }" @5 o) b/ k) o B& W0 U
Retaining mammalian spermatic stem cells0 k" Q1 Y% f7 H$ p9 O. O# o
IV. Ramifications of Developmental Biology2 ~; G) o9 w" \) ]7 h, K
20. An overview of plant development. P( t7 C. z N. J( }
Gamete formation and pollen tube guidance
/ S1 p" T1 O3 U7 R8 k! \5 J' I' pMaternal effects and embryo development
! D3 J! j# J5 zRadial and axial patterning
0 X2 j$ F* }4 \$ QNew model for auxin specification of polarity
& ^* u. a4 f, V' |; w4 _+ c# A! BRoles of microRNAs in plant development
/ e/ }1 K# s. e. s! I( _7 zDorsal–ventral leaf patterning
- C7 O7 b2 l1 D0 N' U7 sLong-distance RNA transport and flowering
. \$ }8 U; S! RFloral meristem specification- F3 v% i& F& L
21. Medical implications of developmental biology: f" U8 h9 J% r5 i& V2 M
Mechanisms of alcohol teratogenesis7 e, ?2 [9 |6 o4 P: u( f+ ?
Effects of endocrine disruptors on human development
3 `, f/ M( H4 Q5 z- {; oNutritional effects of gene methylation and disease susceptibility
9 R2 R" s. ]" g# b h+ kCancer as a disease of development7 Z" W0 E0 s: U* c
Cancer stem cell hypothesis O+ y& |' S. K) ~1 t. A9 x
Developmental approaches to cancer therapy8 z. q8 j; o8 w
Stem cell therapeutics4 e; @# d) o# o9 B$ u
Regenerating human limbs and neurons
) ?$ _) P, F9 ~7 h& p$ c0 P22. Environmental regulation of animal development
: a" m L$ j) v6 X2 n7 Z* {Molecular bases for environmental regulation of gene expression; s5 q& z: B9 B9 p8 C9 [% z
• Importance of symbionts in mammalian gut and immune system- o: p: [/ T- X2 ^! z: k) a# Z& L
development
% Z% k; r k. cSignaling from fetal mammalian lung to initiate labor
) ?" Z5 \$ a: F5 n7 U4 l# |! rThe role of nutrition in the development of the dung beetle
3 Z: T' T9 y) u2 U+ NPredator-induced polyphenism and toxicity testing
, _/ v9 Z* u j h* T; V zGenetic assimilation of environmentally induced traits
, H d. S5 _" Z/ R- @+ H. }+ w23. Developmental mechanisms of evolutionary change* B5 T, S1 B5 y; M6 x3 ? R
Developmental modularity and evolution (stickleback studies)
, I4 i2 M/ e* v+ M5 REvolution by heterochrony, heterotopy, heterometry, heterotypy
6 Z3 a2 u3 H3 K% H8 VBMPs and Darwin’s finches; ]$ n9 l$ a, Q. d5 O' O
Origin of neural crest cells and the origin of jaws
5 k+ j, T" b1 o) a* I% AThe search for the Urbilaterian ancestor |
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发表于 2009-9-25 02:27
发表于 2009-11-19 00:18
