干细胞移植用于肝再生治疗的相关研究进展

guokeyi

4 o& E0 r9 B7 D

4 B. w4 D: E3 K/ w刘晓珑　李波0 }: ?" }  U) w" y; @
　　【摘　要】　　目的　对干细胞移植应用于肝再生治疗的相关研究进展进行综述。　方法　广泛查阅近年的相关文& ?( Q' s$ F" l: @0 n& R4 V
献, 对移植研究中常见的干细胞类别、修复机制、植入途径以及临床相关问题进行综述。　结果　修复肝脏的干细胞可以4 i" m, W  d1 U' }. o
分为肝源性干细胞和非肝源性干细胞; 修复机制主要是融合或转分化; 植入途径以门脉内植入多见。目前仍有许多临床
+ o. D$ U: T! c# u/ r! B) t相关问题限制干细胞移植的应用。　结论　提高干细胞的临床实用性需要更深入的研究。$ F- \/ f. w3 p3 J/ r3 @
【关键词】　　干细胞　　再生医学　　肝脏
: Y! _" ?' ]# r" n$ A中图分类号: Q 813　R65713　　文献标识码:A* P# i: {, m# y9 ]. ^3 W
DEVELOPMENTOF L IVER STEM CELL TRANSPLANTATION FOR L IVER REGENERATIVE TREATMENTöL IU
# E: A; q( R  P" m* LX iaolong , L I B o. D ep artm ent of General S u rg ery , W est Ch ina H osp ital, S ichuan U niversity , Cheng d u S ichuan,
" i( K' v3 M% H8 t610041, P. R. Ch ina. E 2m ail: g x lliu@126. com
8 @6 j) Z3 F3 ^0 ~9 |Corresp ond ing au thor: L I B o, E 2m ail: cd libo@m edm ail. com. cn8 a. x. Z- y3 w8 d) q! T) e
【Abstract】　　Objective　To review the development of the liver stem cell t ransp lant fo r the liver regenerat ive
+ ]& z6 p- e  Ht reatment. 　Methods　The t ransp lantat ion2related art icles about the stem cell classificat ion, repairing mechanism s,
, G3 ~% _; s/ Tadm inist rat ion routes, and exist ing p roblem s in the liver regenerat ive therap ies repo rted in the latest literature w ere
6 C, `! \) h' X! S0 f) gextensively review ed. 　Results　The related liver2repairing stem cells w ere found to be inside and outside the liver,9 w# x# p1 c* ^# J8 Q7 N
i. e. , the hepat ic stem cells and the non2hepat ic stem cells. They could repair the liver by the mechanism of the cell
! Y  r/ U) d% L% d2 R  |fusion o r the cell t ransdifferent iat ion. The stem cells could be adm inist rated via the po rtal vein. How ever, the
% L7 j; o/ d  t- [+ g: _( E' aapp licat ion of the liver stem cell t ransp lant w as rest ricted by many related clinical p roblem s. 　Conclus ion 　Further" F& W6 j+ ^+ P8 R' I) @7 Z0 J- X% a
studies are st ill needed fo r an imp rovement of the clinical feasibility fo r the stem cell t ransp lantat ion, especially fo r the% G% Q# H3 v+ C5 {
liver stem cell t ransp lantat ion.- i4 g+ g, V, {% F% K
【Key words】　　Stem cell　　Regenerat ive medicine　　L iver+ ^7 d5 W2 ]# L9 v
8 G% H/ A5 N6 m: Y& |$ G
附件为pdf全文，感谢原创提供者 ，大家回复之后就可以下载了
4 ?$ b1 g; K5 |8 H% S$ I! D( s
9 ]' v7 L$ v& a

ALLUL

感谢提供的胞友

zyj710

多多支持

gy65120

谢谢

sodoo

在需要，多谢

baixiaodgv

1# guokeyi - u" t! X" f, a- @) }3 n
- d2 y7 [- y5 W% |' H
* V3 T3 v/ `2 @  ~2 E$ a
好东西！！！！拿下了！

lianglei3338

应该很好吧

cjsky3721

kankan

fountaincs

谢谢楼主

wmxd01

1# guokeyi7 G9 w! Y, q7 b
支持一下