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本帖最后由 细胞海洋 于 2010-1-19 08:22 编辑 8 q5 Z2 Q& f4 g& i
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Genes and common diseases presents an up-to-date
3 y$ t2 y( @, |1 Fview of the role of genetics in modern medicine,2 Z3 z2 s7 o5 S- [
reflecting the strengths and limitations of a genetic+ ~4 ] ^. s) s9 K
perspective.5 R6 J) v0 {4 X \* t
The current shift in emphasis from the study of
, ~5 A4 O* E& _- o- Y* wrare single gene disorders to common diseases
; Z; Q; @) h. e) F2 n- n, e& p ?brings genetics into every aspect of modern
# b( s- G" q6 W$ q7 z0 bmedicine, from infectious diseases to therapeutics.
6 U* ?5 o# i1 u. fHowever, it is unclear whether this increasingly
3 H0 ]2 W* M( \2 ]+ Ngenetic focus will prove useful in the face of major4 C7 R6 F% j! O0 K0 d; S2 ?0 e
environmental influences in many common
) W* {2 g/ o7 \+ m/ ]diseases.9 p7 b9 k* C4 ]0 X% C0 l; |
The book takes a hard and self-critical look at
/ c+ x1 E. h. n9 o& `what can and cannot be achieved using a genetic
. a' A7 [$ m% h bapproach and what is known about genetic and2 Y) r. u; Z4 g+ |/ k
environmental mechanisms in a variety of/ ~# j/ Z+ R- j1 S
common diseases. It seeks to clarify the goals of
) O6 Z, N4 P: G% ^, c; a* b9 \1 Ihuman genetic research by providing state-of-the
3 ~& q1 F. M3 R! sart insights into known molecular mechanisms4 `0 e; ?$ A: [
underlying common disease processes while at the
" `. }, w* F% x0 c) E2 ]same time providing a realistic overview of the
2 E: m9 D/ c2 G% K8 c2 D0 Aexpected genetic and psychological complexity.
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