PDF电子书《Epigenetics》C. David Allis 冷泉港出版社 2007 表观遗传学圣经

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, N/ y- F5 u" Y5 LEpigenetics
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$ x# L) X, b5 K" F+ R5 {% kEdited By C. David Allis, The Rockefeller University, New York; - k* @5 ^2 y: M! d2 Q2 z" j
Thomas Jenuwein, Research Institute of Molecular Pathology, Vienna; ) C3 v0 i9 i# w1 K0 g4 s
Danny Reinberg, Howard Hughes Medical Institute/University of Medicine and Dentistry of New Jersey–Robert Wood Johnson Medical School;0 `3 u2 Z+ x# ?
Marie-Laure Caparros, Associate Editor 2 C& o% Q) f; Z/ _
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Description& z8 _$ H/ q9 o0 R$ C
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The regulation of gene expression in many biological processes involves epigenetic mechanisms. In this new volume, 24 chapters written by experts in the field discuss epigenetic effects from many perspectives. There are chapters on the basic molecular mechanisms underpinning epigenetic regulation, discussion of cellular processes that rely on this kind of regulation, and surveys of organisms in which it has been most studied. Thus, there are chapters on histone and DNA methylation, siRNAs and gene silencing; X-chromosome inactivation, dosage compensation and imprinting; and discussion of epigenetics in microbes, plants, insects, and mammals. The last part of the book looks at how epigenetic mechanisms act in cell division and differentiation, and how errors in these pathways contribute to cancer and other human diseases. Also discussed are consequences of epigenetics in attempts to clone animals. This book is a major resource for those working in the field, as well as being a suitable text for advanced undergraduate and graduate courses on gene regulation.
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Contents6 }& B! g4 c* Q5 ^) T* q: p
1. Epigenetics: From Phenomenon to Field
7 _( M6 l1 e4 s, [" [1 ?8 ~" ZD.E. Gottschling9 M* b  E- D; P5 ~
2. A Brief History of Epigenetics5 f+ ]$ F+ Y" x7 J2 a) a* E8 }' x
G. Felsenfeld
3 D7 x  h* h6 k3. Overview and Concepts
8 c+ Y& S3 n* f8 S* a  l& F" ?) ZC.D. Allis, T. Jenuwein, and D. Reinberg
* _  E. a2 j* _, h1 `4. Epigenetics in Saccharomyces cerevisiae
* L! h" U3 z0 ^M. Grunstein and S. Gasser
6 i8 A6 \! ~9 x$ {5. Position Effect Variegation, Heterochro-matin Formation, and Gene Silencing in Drosophila* n3 @4 {9 |2 l$ @7 S$ U" C# J/ V
S.C.R. Elgin and G. Reuter7 m0 i& U& \% W$ e
6. Fungal Models for Epigenetic Research: Schizosaccharomyces pombe and Neurospora crassa
3 W) |8 H6 R0 v* N$ J, c% H% uR.C. Allshire and E.U. Selker
4 T0 p. s' w( Q, A8 q* j$ z. E& u7. Epigenetics of Ciliates
3 J) a  v  R- t; [3 yE. Meyer and D.L. Chalker+ A" w1 D; F& C& ], W0 ~
8. RNAi and Heterochromatin Assembly5 {; p) b4 ?# _$ l" q% U0 v
R. Martienssen and D. Moazed
2 A# m5 F3 K( C1 K) h* s# t* |( i9. Epigenetic Regulation in Plants0 m  B& u( X/ W( z8 ~* F, h+ V% j
M. Matzke and O. Mittelsten Scheid
; ^5 |3 `2 ^/ I# W, B+ V10. Chromatin Modifications and Their Mechanism of Action
, o$ ?" l. k9 l' e& cT. Kouzarides and S.L. Berger! o# k% k2 O4 g
11. Transcriptional Silencing by Polycomb Group Proteins
( Q& z  K( g( G/ jU. Grossniklaus and R. Paro
1 R$ ?# e; {6 y. I12. Transcriptional Regulation by Trithorax Group Proteins
2 i( M% R8 o) y4 UR.E. Kingston and J.W. Tamkun& M* r& C9 i/ @4 ~# x& Q: A$ r4 K
13. Histone Variants and Epigenetics+ V. X( p, W8 X5 J6 ^9 Y: @% V
S. Henikoff and M.M. Smith
' V# e/ q$ ^2 Y1 h6 b4 n! y14. Epigenetic Regulation of Chromosome Inheritance
1 P9 a2 s$ v& d. lG.H. Karpen and R.S. Hawley3 X6 M0 P, O  V7 v
15. Epigenetic Regulation of the X Chromosomes in C. elegans7 O% }0 L8 g, k% V1 |- D
S. Strome and W.G. Kelly
. F% i# R( S) w) j+ ]2 s16. Dosage Compensation in Drosophila
% I8 \" h. r& l* P4 kJ.C. Lucchesi and M.I. Kuroda
0 ~  g7 J6 S' S1 ?/ ?- K7 p9 J! v17. Dosage Compensation in Mammals# i! G0 u! U$ ?
N. Brockdorff and B.M. Turner+ G8 n( g$ V" n. F( F' z: r# E
18. DNA Methylation in Mammals
* q- p! J7 [3 P8 p9 {8 sE. Li and A. Bird
1 a/ G3 t  A, @6 l6 d19. Genomic Imprinting in Mammals5 S# f' s: t  U' t" q+ U* j/ h
D.P. Barlow and M.S. Bartolomei) s5 r! ?; R* S. q5 \1 {* M: T" x+ o
20. Germ Line and Pluripotent Stem Cells
3 b0 H6 n; o0 t7 K1 v; pM.A. Surani and W. Reik4 g" Q/ _5 }# b- d! x3 ?7 G( I
21. Epigenetic Control of Lymphopoiesis
' t5 G: V/ s, q/ fM. Busslinger and A. Tarakhovsky
9 M+ o3 y0 s, E8 f  K- o  E: P22. Nuclear Transplantation and the Reprogramming of the Genome
% N2 h- n7 O7 dR. Jaenisch and J. Gurdon
" ^! d3 Q8 ?. N. o- t/ j* `3 L) D23. Epigenetics and Human Disease
+ Q5 @3 A3 S5 s$ i' ^: c+ }/ Q& [( BH.Y. Zoghbi and A.L. Beaudet& e) G! ]5 C! s0 y/ y
24. Epigenetic Determinants of Cancer4 t2 D+ e# D& h: ?% s; T* z4 q, t6 c
S.B. Baylin and P.A. Jones
# G6 F7 |' L, _Appendices3 Y9 N. f7 L( k1 t
Index
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游客，如果你要查看本帖隐藏内容请回复

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回复 50# hellocell
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/ M# }/ Q( }. F7 V: W" O* ]呵呵，新人，握爪！9 ~' }9 q- R6 c7 _
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我每个附件只收费5个包子，至于多收取的，是系统BUG。" B; N8 c1 {6 }- C% I. j% o

6 J9 T# O# i9 G+ @' Q6 _这本书，文件大，清晰度差，当初我通过各种渠道，好不容易才找到这个质量一般的版本；本来是想自己看看就算了，因为手头有中文翻译的纸质版，来点影印版，提高自己的专业英语水平。0 b$ z- q) s# _; z

, O3 v: L; J) \# t大家有兴趣就下载来看看，没兴趣就绕开。' ]& H0 U% `' k) a3 I8 _; w
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希望不仅仅是下载来填充你的电子图书库，阅读，并从中学习到知识，才不枉费大家的包子。3 _# l2 x( G! B- D! m

' n8 G/ u& T7 H当然，最欢迎的是你自己通过网络检索一下，看看，能否找到一个更好的版本；或者，你买科学出版社的影印版，翻译版。
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% }( [$ F& A3 M) d* Z# i) U2 m再次握爪！

芷瞻

你好！是完整的PDF格式电子书，但是，清晰度有待提高。7 x, H. H+ [, V  ^& ]3 V5 l
祝好！
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回复 86# yusheen

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回复 169# hndxws
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( u0 u/ b; r, z* k6 c: I6 a' B1 E0 m- G看仔细，如果真有问题，站内短信我，谢谢！

芷瞻

嗯，文件比较大

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回复 229# heart1804
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. W5 ^! S( M4 T* {清晰度还可以，当然，不是很完美，将就着看吧