标题: Adult mouse bone marrow stem cells can become cells of the nervous system [打印本页] 作者: bobo 时间: 2008-12-31 00:33 标题: Adult mouse bone marrow stem cells can become cells of the nervous system
日期: 2003-08-19 今日/总浏览: 1/435 & h% |- l! G! c; X, i & T& Q/ R/ V, ] / f' x& {+ @) ?- s7 U5 v5 k, S/ D& e9 ^2 q3 r. Z. c' ]* V
* s. E* ]; {5 }9 bUniversityofMinnesotaresearchersshowthatadultbonemarrowstemcellscanbeinducedtodifferentiateintocellsofthemidbrain.Thefindings,publishedintheonlineearlyeditionoftheProceedingsoftheNationalAcademyofSciences,suggestthatadultbone-marrow-derivedstemcellsmayonedaybeusefulfortreatingdiseasesofthecentralnervoussystem,includingParkinson'sdisease. 4 B! Y* U3 J8 b$ WThepotentialoftheseadultstemcells,termedmultipotentadultprogenitorcells(MAPCs),werethesubjectofresearchreportedinNatureinJune2002.Today'spublishedresearchfindingsshowspecificcelldifferentiationforaspecificgoal.Whilethistypeofcelldifferentiationhasbeenshowntooccurfromembryonicandneuralstemcells,thisisthefirsttimeadultbone-marrow-derivedcellshavebeenshowntogeneratedopaminelikeneurons.6 v7 K# l6 K" X0 ~
We'reabletoshowinvitrogenerationoffunctionaldopamineproducingcellsfromadultbonemarrowstemcellsneededfortherapyofParkinson's,saidleadinvestigatorCatherineVerfaillie,M.D.,directoroftheuniversity'sStemCellInstitute.ThisfurtherprovessimilarityoftheMAPCswithembryonicstemcells. 7 l+ x0 X5 {4 U) h7 [4 _Again,whileadultstemcellsholdgreatpromise,sidebysidecomparisonofadultandembryonicstemcellsmustbedonetodeterminewhichstemcellsaremostusefulintreatingaparticulardisease,saidVerfaillie.4 W' p7 O# n* Z7 E s: F9 p" A
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来源: University of Minnesota & v; E5 @' S Z# D& Y1 z) D发布者: 亦云